{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T14:26:52Z","timestamp":1780583212617,"version":"3.54.1"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T00:00:00Z","timestamp":1689292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Female stress urinary incontinence (SUI) is considered a major public health issue. Physical therapy is an important conservative treatment; however, it is primarily limited by poor long\u2010term compliance. Furthermore, surgical treatment entails significant risks. Therefore, new treatment techniques must be identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the use of laser therapy and pelvic floor (PF) physical therapy for treating postmenopausal women with SUI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This pilot study enrolled 40 women with a clinical and urodynamic diagnosis of SUI who were randomized into two groups: those who received erbium\u2010doped yttrium\u2013aluminum\u2013garnet (Er:YAG) laser therapy implemented over three sessions with a 1\u2010month interval (<jats:italic>n<\/jats:italic>\u2009=\u200920) and those who received physical therapy with supervision twice a week for 3 months (<jats:italic>n<\/jats:italic>\u2009=\u200920). In total, 16 women completed the treatment in each group. The patients were assessed for PF function using the modified Oxford scale and for pelvic organ prolapse using the Pelvic Organ Prolapse Quantification System. The 1\u2010h pad test and quality of life questionnaires, King's Health Questionnaire (KHQ), and Incontinence Quality of Life (IQOL) were also administered. Patients were re\u2010evaluated at 1, 3, 6, and 12 months after treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean patient age was 62.7\u2009\u00b1\u20099.1 and 57.9\u2009\u00b1\u20096.1 years, median Oxford score at baseline was 3 (2\u20134.5) and 4 (3\u20134), mean IQOL score was 79.8\u2009\u00b1\u200917 and 74.6\u2009\u00b1\u200918 for physical therapy group (PTG) and laser group (LG), respectively. For the amount of urine leak in the 1\u2010h\u00a0pad test evaluation, we found significance for the interaction of group and time points only for the Laser intragroup. The cure rate, that is, the rate of reaching an insignificant score in the pad test, at 6 and 12 months was 43.75% and 50% in PTG and 62.5% and 56.25% in the LG, respectively (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). IQOL scores demonstrated considerable improvement in both groups (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). Upon comparing the initial and follow\u2010up results, the LG showed an improvement at all consultations, whereas the PTG showed improvements at 1, 3, and 6 months but not at 12 months after treatment. KHQ analysis revealed a considerable improvement in the quality of life (QOL) of patients over time, with no substantial difference between the groups. QOL comparison before and after treatment revealed that the vaginal LG improved more consistently in some domains. Only the PTG showed a significant increase in the mean Oxford score from pretreatment to 1 and 3 months after treatment (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 and <jats:italic>p<\/jats:italic>\u2009=\u20090.002, respectively). However, no statistically significant difference was observed between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both treatments are safe and have a positive influence on the impact of UI on patients'\u00a0QOL. The laser caused a greater reduction in the urinary loss, as measured using the weight of pad test, at 6\u2010month and 12\u2010month after treatment without difference with PTG at the end of the follow\u2010up.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.25244","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T08:23:55Z","timestamp":1689323035000},"page":"1445-1454","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["A randomized trial comparing vaginal laser therapy and pelvic floor physical therapy for treating women with stress urinary incontinence"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6348-1791","authenticated-orcid":false,"given":"Luc\u00edlia C.","family":"da Fonseca","sequence":"first","affiliation":[{"name":"Gynecology Department, Medical School,\u00a0Urogynecology Division of Obstetrics Universidade de S\u00e3o Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Bacchi Ambrosano","family":"Giarreta","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Speech and Occupational Therapy, Medical School Universidade de S\u00e3o Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thais V.","family":"Peterson","sequence":"additional","affiliation":[{"name":"Gynecology Department, Medical School,\u00a0Urogynecology Division of Obstetrics Universidade de S\u00e3o Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscila Katsumi Matsuoka","family":"Locali","sequence":"additional","affiliation":[{"name":"Gynecology Department, Medical School,\u00a0Urogynecology Division of Obstetrics Universidade de S\u00e3o Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmund C.","family":"Baracat","sequence":"additional","affiliation":[{"name":"Gynecology Department, Medical School,\u00a0Urogynecology Division of Obstetrics Universidade de S\u00e3o Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0678-0186","authenticated-orcid":false,"given":"Elizabeth A. Gon\u00e7alves","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Gynecology Department, Medical School,\u00a0Urogynecology Division of Obstetrics Universidade de S\u00e3o Paulo  Sao Paulo Brazil"},{"name":"Department of Physical Therapy, Speech and Occupational Therapy, Medical School Universidade de S\u00e3o Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Milhem","family":"Haddad","sequence":"additional","affiliation":[{"name":"Gynecology Department, Medical School,\u00a0Urogynecology Division of Obstetrics Universidade de S\u00e3o Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-0976-9"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)02243-4"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-020-04237-0"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-016-1884-0"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1989.tb01570.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001920200020"},{"key":"e_1_2_10_8_1","first-page":"583","article-title":"Decreased collagen synthesis in stress\u2010incontinent women","volume":"84","author":"Falconer C","year":"1994","journal-title":"Obstet Gynecol"},{"key":"e_1_2_10_9_1","article-title":"Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary incontinence in women","volume":"2015","author":"Ayeleke RO","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19052789"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000001206"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-020-04548-2"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10517-017-3650-0"},{"key":"e_1_2_10_14_1","first-page":"46","article-title":"Novel minimally invasive VSP Er:YAG laser treatments in gynecology","volume":"1","author":"Vizintin Z","year":"2012","journal-title":"J Laser Health Acad"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2018.03.038"},{"key":"e_1_2_10_16_1","volume-title":"Urodynamic Testing and Interpretation","author":"Yao M","year":"2023"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70243-0"},{"key":"e_1_2_10_18_1","first-page":"40","article-title":"Female pelvic floor assessment: the laycock ring of continence","volume":"1994","author":"Laycock J","year":"1994","journal-title":"J Natl Women Health Group Aust Physiother Assoc"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-72032005000500002"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-0916-8"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.24350"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2009.03.003"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-31802007000500003"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.21104"},{"key":"e_1_2_10_25_1","article-title":"Lifestyle interventions for the treatment of urinary incontinence in adults","volume":"2015","author":"Imamura M","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/1576359"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.25244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T13:17:25Z","timestamp":1706620645000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.25244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,14]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1002\/nau.25244"],"URL":"https:\/\/doi.org\/10.1002\/nau.25244","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,14]]},"assertion":[{"value":"2023-02-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}