{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:50:55Z","timestamp":1792601455114,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T00:00:00Z","timestamp":1688774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To identify the clinical and urodynamic risk factors associated with the development of recurrent febrile urinary tract infections (FUTIs) in children with neurogenic bladder (NB) who perform clean intermittent catheterization\u00a0(CIC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Children with NB receiving CIC were prospectively enrolled from January to December 2019 and followed up prospectively for 2 years. All data were compared between occasional (0\u20131 FUTI) and recurrent FUTIs (\u22652 FUTI) groups. In addition, the risk factors for recurrent FUTIs in children were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Complete data from 321 children were analyzed. Occasional FUTIs occurred in 223 patients, and 98 patients experienced recurrent FUTIs. Univariate and multivariate analyses, showed late\u2010initiation and low\u2010frequency CIC, vesicoureteral reflux (VUR), small bladder capacity and low compliance, and detrusor overactivity were associated with an increased risk of recurrent FUTIs. Children with high\u2010grade VUR (grades IV\u2012V) had a higher risk of recurrent FUTIs than those with low\u2010grade VUR (grades I\u2012III) (odds ratio [OR]: 26.95 vs.\u00a0OR: 4.78,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study suggests that late\u2010initiation and low\u2010frequency CIC, VUR, small bladder capacity and low compliance, and detrusor overactivity were associated with recurrent FUTIs in patients with NB. In addition, high\u2010grade VUR is a crucial risk factor for recurrent FUTIs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.25245","type":"journal-article","created":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T05:39:15Z","timestamp":1688794755000},"page":"1485-1490","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Risk factors associated with recurrent febrile urinary tract infection in children with neurogenic bladder who perform clean intermittent catheterization"],"prefix":"10.1002","volume":"42","author":[{"given":"Guanglun","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function Shenzhen Children's Hospital Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Shenzhen Children's Hospital Shenzhen China"},{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function Shenzhen Children's Hospital Shenzhen China"},{"name":"Department of Clinical Laboratory Shenzhen Children's Hospital Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function Shenzhen Children's Hospital Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoulin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function Shenzhen Children's Hospital Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7947-1316","authenticated-orcid":false,"given":"Jinjun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function Shenzhen Children's Hospital Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22378"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2015.05.006"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.5527\/wjn.v10.i4.37"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-017-2356-7"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70477-9"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2019.2504"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23897"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/20469047.2017.1351745"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2021.12.037"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)63403-7"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2004.00943.x"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.4321\/S0004-06142008000200015"},{"issue":"1","key":"e_1_2_11_14_1","first-page":"394","article-title":"Effect of a single\u2010use sterile catheter for each void on the frequency of bacteriuria in children with neurogenic bladder on intermittent catheterization for bladder emptying","volume":"168","author":"Schlager TA","year":"2001","journal-title":"Pediatrics"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2016.12.049"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-019-02743-5"},{"issue":"3","key":"e_1_2_11_17_1","first-page":"153","article-title":"Vesicoureteral reflux and bladder dysfunction","volume":"1","author":"Lee H","year":"2012","journal-title":"Transl Androl Urol"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2018.10.096"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.12.056"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2021.12.002"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.14186"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.25245","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T08:17:15Z","timestamp":1706602635000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.25245"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,8]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1002\/nau.25245"],"URL":"https:\/\/doi.org\/10.1002\/nau.25245","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,8]]},"assertion":[{"value":"2023-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}