{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T10:28:42Z","timestamp":1782988122275,"version":"3.54.5"},"reference-count":53,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T00:00:00Z","timestamp":1706572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["40\u201046300\u201098\u201011103"],"award-info":[{"award-number":["40\u201046300\u201098\u201011103"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>A congenital disease is for life. Posterior hypospadias, the severe form of hypospadias with a penoscrotal, scrotal, or perineal meatus, is a challenging condition with a major impact on lifelong quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>Our network meeting is aimed to identify what is currently missing in the lifelong treatment of posterior hypospadias, to improve care, quality of life, and awareness for these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The network meeting \u201cLifelong Posterior Hypospadias\u201d\u00a0in Utrecht, The Netherlands was granted by the European Joint Programme on Rare Diseases\u2013Networking Support Scheme. There was a combination of interactive sessions (hackathons) and lectures. This paper can be regarded as the last phase of the hackathon.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Surgery for hypospadias remains challenging and complications may occur until adulthood. Posterior hypospadias affects sexual function, fertility, and hormonal status. Transitional care from childhood into adulthood is currently insufficiently established. Patients should be more involved in defining desired treatment approach and outcome measures. For optimal outcome evaluation standardization of data collection and registration at European level is necessary. Tissue engineering may provide a solution to the shortage of healthy tissue in posterior hypospadias. For optimal results, cooperation between basic researchers from different centers, as well as involving clinicians and patients is necessary.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>To improve outcomes for patients with posterior hypospadias, patient voices should be included and lifelong care by dedicated healthcare professionals guaranteed. Other requirements are joining forces at European level in uniform registration of outcome data and cooperation in basic research.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.25305","type":"journal-article","created":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T15:36:22Z","timestamp":1706628982000},"page":"1097-1103","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["What should be next in lifelong posterior hypospadias: Conclusions from the 2023 ERN eUROGEN and EJP\u2010RD networking meeting"],"prefix":"10.1002","volume":"43","author":[{"given":"Rianne J. M.","family":"Lammers","sequence":"first","affiliation":[{"name":"Department of Urology University Medical Center Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Tsachouridis","sequence":"additional","affiliation":[{"name":"Department of Urology University Medical Center Utrecht Utrecht The Netherlands"},{"name":"Department of Pediatric Urology Wilhemina Kinderziekenhuis Utrecht The Netherlands"},{"name":"Regenerative Medicine Center Utrecht Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie K.","family":"Andersson","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Sahlgrenska Academy, Women's and Children's Health Queen Silvia's Children's Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Dormeus","sequence":"additional","affiliation":[{"name":"Department of Urology University Medical Center Utrecht Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa O.","family":"Ekerhult","sequence":"additional","affiliation":[{"name":"Department of Urology Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miko\u0142aj","family":"Frankiewicz","sequence":"additional","affiliation":[{"name":"Department of Urology Medical University of Gdansk Gda\u0144sk Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Callum J.","family":"Gunn","sequence":"additional","affiliation":[{"name":"Department of Bioethics and Health Humanities, Julius Center University Medical Center Utrecht Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Matuszewski","sequence":"additional","affiliation":[{"name":"Department of Urology Medical University of Gdansk Gda\u0144sk Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keetje L.","family":"de Mooij","sequence":"additional","affiliation":[{"name":"Department of Pediatric Urology Wilhemina Kinderziekenhuis Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rogier P. J.","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Department of Pediatric Urology Wilhemina Kinderziekenhuis Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel I. A.","family":"Wyndaele","sequence":"additional","affiliation":[{"name":"Department of Urology University Medical Center Utrecht Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhentao","family":"Xing","sequence":"additional","affiliation":[{"name":"Department of Urology University Medical Center Utrecht Utrecht The Netherlands"},{"name":"Regenerative Medicine Center Utrecht Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laetitia M. O.","family":"De Kort","sequence":"additional","affiliation":[{"name":"Department of Urology University Medical Center Utrecht Utrecht The Netherlands"},{"name":"Regenerative Medicine Center Utrecht Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3183-8901","authenticated-orcid":false,"given":"Petra","family":"de Graaf","sequence":"additional","affiliation":[{"name":"Department of Urology University Medical Center Utrecht Utrecht The Netherlands"},{"name":"Regenerative Medicine Center Utrecht Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,30]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"RadmayrCB.EAU guidelines on paediatric urology.2023.https:\/\/uroweb.org\/guidelines\/paediatric-urology"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2016.05.002"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.179178"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0b013e328357bc9e"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.03.073"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2014.00002"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10916-016-0532-3"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsurg.2020.04.005"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2015.09.005"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2010.112"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.14967"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000181506.97839.b0"},{"key":"e_1_2_9_13_2","unstructured":"Discussion1538\u20101539."},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7796.192097"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare8010032"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1937586719887709"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2013.01.015"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.05.060"},{"key":"e_1_2_9_18_2","unstructured":"Discussion1084."},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/hex.12873"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.2196\/15847"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-14-89"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-063507"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41687-023-00566-y"},{"key":"e_1_2_9_24_1","unstructured":"OrtacM EkerhultTO ZhaoW AtalaA. Tissue engineering graft for urethral reconstruction: is it ready for clinical application? 2023;2149\u20103235 (Print)."},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2012.02659.x"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)62354-9"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/term.2487"},{"issue":"12","key":"e_1_2_9_28_1","first-page":"1335","article-title":"The multilayered structure of the human corpus spongiosum","volume":"33","author":"Graaf P","year":"2018","journal-title":"Histol Histopathol"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2016.02.007"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)62711-3"},{"key":"e_1_2_9_30_2","unstructured":"Discussion1137."},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2020.04.014"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tec.2019.0280"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10508-016-0843-y"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10508-021-01999-6"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsxm.2020.03.015"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1037\/fam0000407"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsm.12942"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2015.09.012"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsxm.2020.04.002"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2018.06.032"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2011.02.008"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.13229"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000002738"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2016.08.014"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2017.02.005"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2020.05.070"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.5227"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.12.011"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0000000000000771"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-021-01035-z"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-020-03111-4"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.25305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T03:26:43Z","timestamp":1730518003000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.25305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,30]]},"references-count":53,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/nau.25305"],"URL":"https:\/\/doi.org\/10.1002\/nau.25305","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,30]]},"assertion":[{"value":"2023-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}