{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T22:11:02Z","timestamp":1794003062529,"version":"4.8.0"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T00:00:00Z","timestamp":1717459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the association between overactive bladder syndrome (OAB) and the metabolic syndrome (MetS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>A population\u2010based study was conducted to compare OAB patients with age\u2010, sex\u2010 and ethnicity\u2010matched control subjects regarding the prevalence of the parameters of the MetS, with respect to obesity, hyperlipidemia, hypertension and diabetes mellitus. The characteristics of the OAB population were assessed. Adjusted odds ratios (OR) were calculated by logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>110\u2009024 OAB patients and 220\u2009455 controls. were identified. OAB was associated with a higher prevalence of MetS (35.4% vs. 27.5%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The fully adjusted OR for MetS in patients with OAB compared to controls was 1.44; 95% confidence interval (CI) 1.42\u22121.46; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001. Among metabolic parameters, obesity was found to be the strongest factor associated with OAB (OR 1.55, 95% CI 1.53\u22121.58, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and higher high\u2010density lipoprotein cholesterole\u00a0levels (&gt;50) had a protective effect on the risk of OAB (OR 0.75, 95% CI 0.73\u22120.76, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Data from this cohort suggest that OAB is positively associated with MetS. Clinicians approaching patients with OAB should be aware of this association. A multimodal treatment focusing on the MetS may be considered in these patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.25521","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T17:55:30Z","timestamp":1717523730000},"page":"1809-1816","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Increased prevalence of metabolic syndrome in female patients with overactive bladder: A population\u2010based study"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9500-7584","authenticated-orcid":false,"given":"Omer","family":"Anis","sequence":"first","affiliation":[{"name":"Department of Urology Sheba Medical Center Tel\u2010Hashomer Israel"},{"name":"The Mina and Everard Goodman Faculty of Life Sciences Bar\u2010Ilan University Ramat Gan Israel"},{"name":"Section of Female Pelvic Medicine and Reconstructive Surgery, Glickman Urological and Kidney Institute, 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