{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:11:35Z","timestamp":1792761095335,"version":"4.5.0"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify factors that can predict both test phase and midterm success of sacral neuromodulation (SNM) in refractory non\u2010neurogenic overactive bladder syndrome (nnOAB) based on preoperative clinical and urodynamic data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We conducted a two\u2010center retrospective study and included all individuals with nnOAB who underwent a test phase between 2005 and 2021, with or without subsequent implantation of an SNM device. Only those with preoperative urodynamic assessment data were included. SNM success was defined as \u200950% improvement in one of the bladder diary parameters, associated with \u200950% symptom improvement. Individuals underwent follow\u2010up evaluation at 2 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 191 individuals were included (163 women), 69% of whom underwent SNM device implantation. At the preoperative urodynamic exam, 115 individuals had detrusor overactivity (DO). Test phase success was associated with younger age (<jats:italic>p<\/jats:italic>\u2009=\u20090.009). 24\u2010month SNM success was associated with lower maximal detrusor pressure at DO (Pdet max DO) at baseline (<jats:italic>p<\/jats:italic>\u2009=\u20090.045). Other predictive factors for success at 2 years were female (<jats:italic>p<\/jats:italic>\u2009=\u20090.03), a history of stress incontinence surgery (<jats:italic>p<\/jats:italic>\u2009=\u20090.01), a low maximum urethral closure pressure (MUCP) (<jats:italic>p<\/jats:italic>\u2009=\u20090.04), a low volume at first DO (VFDO) (<jats:italic>p<\/jats:italic>\u2009=\u20090.03), and a high maximum cystometric capacity (MCC) (<jats:italic>p<\/jats:italic>\u2009=\u20090.03). We developed a tool to predict success at 2 years. The following threshold values were significantly associated with treatment success: MUCP\u2009&lt;\u200958\u2009cmH<jats:sub>2<\/jats:sub>O, VFDO\u2009&lt;\u2009170\u2009mL, and MCC\u2009&gt;\u2009254\u2009mL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Age predicted test phase success. Pdet max DO, gender, history of incontinence surgery, high MUCP, MCC, and VFDO predicted midterm success of SNM in people with nnOAB.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.70041","type":"journal-article","created":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T14:10:01Z","timestamp":1742825401000},"page":"997-1006","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Development of a Predictive Tool for Midterm Success of Sacral Neuromodulation in Non\u2010Neurogenic Overactive Bladder Syndrome"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3339-6329","authenticated-orcid":false,"given":"Samy","family":"Hafez","sequence":"first","affiliation":[{"name":"Department of Urology Centre Hospitalo\u2010Universitaire de Nantes Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgane","family":"Pere","sequence":"additional","affiliation":[{"name":"Centre Hospitalo\u2010Universitaire de Nantes, Direction Recherche Innovation, Plateforme M\u00e9thodologie et Biostatistique Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Olivier","sequence":"additional","affiliation":[{"name":"Department of Urology Centre Hospitalo\u2010Universitaire de Lille Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Carolus","sequence":"additional","affiliation":[{"name":"Department of Urology Centre Hospitalo\u2010Universitaire de Lille Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Liesse","family":"De Guerry","sequence":"additional","affiliation":[{"name":"Department of Urology Centre Hospitalo\u2010Universitaire de Nantes Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Rigaud","sequence":"additional","affiliation":[{"name":"Department of Urology Centre Hospitalo\u2010Universitaire de Nantes Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Biardeau","sequence":"additional","affiliation":[{"name":"Department of Urology Centre Hospitalo\u2010Universitaire de Lille Lille France"},{"name":"Inserm UMR\u2010S1172 LilNCog, Lille Neuroscience and Cognition Universit\u00e9 de Lille Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Aim\u00e9e","family":"Perrouin\u2010Verbe","sequence":"additional","affiliation":[{"name":"Department of Urology Centre Hospitalo\u2010Universitaire de Nantes Nantes France"},{"name":"INSERM, The Enteric Nervous System in Gut and Brain Disorders Nantes Universit\u00e9 Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,24]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.10052"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23768"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.purol.2016.04.002"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.purol.2020.09.002"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.02.038"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23515"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.06.142"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20786"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2223-4683.2015.12.01"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23422"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.07.010"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2021.06.013"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22707"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.25346"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000513937"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-023-04638-y"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23383"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/ner.12695"},{"key":"e_1_2_14_20_1","unstructured":"I.LankhamandM.Slaughter.Simple and Efficient Bootstrap Validation of Predictive Models Using SAS\/STAT\u00ae Software. 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