{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:59:00Z","timestamp":1755219540550,"version":"3.43.0"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T00:00:00Z","timestamp":1747872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>This study aimed to identify potential predictive factors of nocturia with \u2265\u20092 nightly voids, with a particular focus on nocturnal polyuria (NP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 154 men aged 42\u201388\u2009years were enrolled. Participants were categorized into two groups based on the number of nighttime voids: Group A (&lt;\u20092 voids\/night, <jats:italic>n<\/jats:italic>\u2009=\u200979) and Group B (\u2265\u20092 voids\/night, <jats:italic>n<\/jats:italic>\u2009=\u200975), including a subgroup with NP (<jats:italic>n<\/jats:italic>\u2009=\u200961). All participants completed 3\u2010day frequency\u2010volume charts and self\u2010administered questionnaires assessing oral dryness using a visual analog scale and subjective sleep quality. Multivariable logistic regression analysis was performed to identify predictors of nocturia with \u2265\u20092 voids.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared with Group A, Group B demonstrated significantly lower total scores on the Nocturia\u2010Specific Quality of Life Questionnaire (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), higher Overactive Bladder Symptom Scores (OABSS) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), shorter time to first nocturnal void (u\u2010HUS; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), greater nocturnal oral dryness (<jats:italic>p<\/jats:italic>\u2009=\u20090.004), and poorer subjective sleep quality (<jats:italic>p<\/jats:italic>\u2009=\u20090.006). There were no significant differences in the number of medications taken between groups. Among participants with NP, those with \u2265\u20092 voids exhibited significantly poorer sleep quality (<jats:italic>p<\/jats:italic>\u2009=\u20090.007), increased nocturnal oral dryness (<jats:italic>p<\/jats:italic>\u2009=\u20090.030), and shorter u\u2010HUS (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) compared with those with &lt;\u20092 voids. Multivariable analysis identified nocturnal oral dryness (<jats:italic>p<\/jats:italic>\u2009=\u20090.015), shortened u\u2010HUS (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and elevated OABSS (<jats:italic>p<\/jats:italic>\u2009=\u20090.045) as independent predictors of nocturia with \u2265\u20092 voids.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Increased nocturnal oral dryness and shortened u\u2010HUS are associated with nocturia involving \u2265\u20092 nighttime voids and may negatively impact quality of life, particularly in patients with NP. These findings highlight the clinical importance of addressing dry mouth as a significant comorbidity in older adults with nocturia.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.70081","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T05:16:13Z","timestamp":1747890973000},"page":"1318-1324","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Correlates of Nocturia With \u2265\u20092 Nighttime Voids in Older Adults: Associations With Dry Mouth and Sleep Quality"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-1544-0224","authenticated-orcid":false,"given":"Osamu","family":"Natsume","sequence":"first","affiliation":[{"name":"Department of Urology Uda City Hospital Uda Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1150-1298","authenticated-orcid":false,"given":"Nobutaka","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University Kashihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1507-2464","authenticated-orcid":false,"given":"Kiyohide","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University Kashihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,22]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22724"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2008.04.002"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.2003.04062.x"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2003.04527.x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)00603-8"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000000683"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1992.tb03645.x"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.05.093"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.09.108"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/02813439209014044"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.2005.00087.x"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.10053"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2006.06499.x"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(89)90047-4"},{"key":"e_1_2_12_16_1","first-page":"755","article-title":"Development of the Japanese Version of the Pittsburgh Sleep Quality Index","volume":"13","author":"Doi Y.","year":"1998","journal-title":"Journal of Psychiatry Treatment. 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