{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T13:18:39Z","timestamp":1776604719113,"version":"3.51.2"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Conventional urodynamic studies have been variably reported to be unable to reproduce a patients' symptoms (3.5%\u201368%) and detrusor overactivity (DO) can be missed in up to 54% of cases. Tertiary referral centers have reported successful diagnostic yield of ambulatory urodynamic studies (AUDS) in 74%\u201398%. However, it's clinical utility has been questioned. We aimed to evaluate the diagnostic and therapeutic outcomes of our tertiary AUDS service.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review was undertaken of consecutive patients attending for AUDS, including local and regional referrals. Data was collected on patient demographics, indication, urodynamic diagnosis, and subsequent management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and forty two AUDS procedures were evaluated. Median age was 59 years (range 23\u201390); 18% were male and 42% regional referrals. A urodynamic diagnosis was made in 80% patients. Thirty\u2010five percent were diagnosed with idiopathic detrusor overactivity, 32% with stress urinary incontinence and 11% were found to have mixed urinary incontinence. There was a change from baseline urodynamic diagnosis in 69%. Of those with follow\u2010up information available (<jats:italic>n<\/jats:italic>\u2009=\u200981), 74% had a change in management, including 59% considered for surgical intervention. No patients went on to require further urodynamic investigation when symptoms were not reproduced on AUDS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>AUDS successfully diagnosed 80% of patients referred with inconclusive conventional UDS, translating to change in management and surgical intervention. AUDS is an important tool in select patient groups, to reproduce symptoms and guide management, where conventional UDS has failed.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nau.70111","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T00:35:23Z","timestamp":1751589323000},"page":"1491-1497","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Diagnostic and Therapeutic Outcomes of Ambulatory Urodynamics in a Tertiary Referral Center"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7457-9545","authenticated-orcid":false,"given":"Charlotte Mary","family":"Hughes","sequence":"first","affiliation":[{"name":"Department of Urology Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8554-4335","authenticated-orcid":false,"given":"Nikita Rajiv","family":"Bhatt","sequence":"additional","affiliation":[{"name":"Department of Urology Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna Catherine Georgina","family":"Penfold","sequence":"additional","affiliation":[{"name":"Department of Urology Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily Jane","family":"Speck","sequence":"additional","affiliation":[{"name":"Department of Urology Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7719-4366","authenticated-orcid":false,"given":"Thomas Giles","family":"Gray","sequence":"additional","affiliation":[{"name":"Department of Gynaecology Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilias","family":"Giarenis","sequence":"additional","affiliation":[{"name":"Department of Gynaecology Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah Jane","family":"Wood","sequence":"additional","affiliation":[{"name":"Department of Urology Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte Elizabeth","family":"Dunford","sequence":"additional","affiliation":[{"name":"Department of Urology Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth Danielle","family":"Doherty","sequence":"additional","affiliation":[{"name":"Department of Urology Norfolk and Norwich University Hospital Norwich UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,3]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"358","volume-title":"ICS Standards 2019","author":"International Continence Society","year":"2019"},{"key":"e_1_2_11_3_1","volume-title":"Urinary Incontinence and Pelvic Organ Prolapse in Women: Management [NG123]","author":"National Institute for Clinical Excellence","year":"2019"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.10066"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.24153"},{"key":"e_1_2_11_6_1","volume-title":"Non\u2010Neurogenic Female LUTS","author":"EAU Guidelines E","year":"2024"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-015-2817-3"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65545-0"},{"issue":"6","key":"e_1_2_11_9_1","doi-asserted-by":"crossref","first-page":"354","DOI":"10.48083\/MHMI1178","article-title":"Ambulatory Urodynamic Findings Change Patient Outcomes","volume":"2","author":"Axell R. 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