{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:10:19Z","timestamp":1778818219243,"version":"3.51.4"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate how acupuncture alleviates Postpartum Urinary Retention (PUR) by identifying key acupoints and biological mechanisms, we combine the implementation of association rule mining and running a systematic review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic literature review was conducted, and association rule mining was performed with IBM SPSS Modeler 25.0. A protein\u2010protein interaction (PPI) network was constructed using UniProt\u2010standardized gene targets. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses elucidated underlying mechanisms. This study utilized a single\u2010center clinical trial carried out at Anhui Provincial Maternal and Child Health Hospital, spanning from January 2019 to January 2025. It involved a comparative analysis between two cohorts: the intervention group, which received acupuncture combined with conventional care, and the control group, which underwent placebo acupuncture alongside standard care. Time to first urination, residual urine volume, catheterization rate\/duration, symptoms, postpartum hemorrhage, infections, quality of life score, anxiety\/depression level score, and adverse events are monitored to determine whether they impact.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Association rule mining identified four key acupoints (Sanyinjiao SP6, Zhongji CV3, Zusanli ST36, Yinlingquan SP9), with ST36, SP9, and SP6 strongly linked to genes such as TP53, ERBB2, CTNNB1, and CGFR. Acupuncture regulates functions via PI3K\u2010Akt, FoxO, and ErbB pathways. The treatment group showed significantly better outcomes in all measured parameters except adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Acupuncture effectively reduces the PUR incidences through precise acupoint targeting, minimizing trauma, and enhancing postpartum care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.70253","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T21:27:07Z","timestamp":1773005227000},"page":"746-764","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of the Therapeutic Efficacy of Acupuncture in Treating Postpartum Urinary Retention: A Comprehensive Approach Integrating Systematic Review and Association Rule Analysis"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3379-0830","authenticated-orcid":false,"given":"Xi","family":"Ye","sequence":"first","affiliation":[{"name":"Qinghai University Affiliated Clinical Medical College Xining Qinghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuling","family":"Wu","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian","family":"Le","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department The Sixth People's Hospital affiliated with Shanghai Jiao Tong University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqun","family":"Su","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Jingdong Medical Zone of the General Hospital of the People's Liberation Army Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bingbing","family":"Wang","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yufen","family":"Long","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiqing","family":"Song","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Li","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjie","family":"Ding","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunyan","family":"Wang","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruli","family":"Wang","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongrong","family":"Lu","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojie","family":"Sun","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Hebei Children's Hospital Shijiazhuang Hebei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjie","family":"Cao","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Shanghai Changning District Maternity and Child Health Hospital associated with East China Normal University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miaoqi","family":"Jiao","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Qingdao Ruiside Hospital Qingdao Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanyue","family":"Zhang","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Peking University Third Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Xu","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department The Sixth People's Hospital affiliated with Shanghai Jiao Tong University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingao","family":"Zheng","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruyuan","family":"Ding","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yadan","family":"Shen","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Zhuxian County Zhugezhuang Town Health Center in Baoding City Baoding Hebei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yali","family":"Pan","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department The Sixth People's Hospital affiliated with Shanghai Jiao Tong University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiwei","family":"Wang","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoli","family":"Ren","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Zhuolu County Community Health Service Center in Zhangjiakou City Zhangjiakou Hebei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenyu","family":"Mu","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Xuzhou Medical University Affiliated Hospital Xuzhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangfeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Le","family":"Yu","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Anhui Province Maternal and Child Health Hospital Hefei Anhui China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuanxuan","family":"Hong","sequence":"additional","affiliation":[{"name":"Qinghai University Affiliated Clinical Medical College Xining Qinghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Runzhi","family":"Shi","sequence":"additional","affiliation":[{"name":"Qinghai University Affiliated Clinical Medical College Xining Qinghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8348-1684","authenticated-orcid":false,"given":"Fei","family":"Wang","sequence":"additional","affiliation":[{"name":"Qinghai University Affiliated Clinical Medical College Xining Qinghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liehong","family":"Wang","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Qinghai Red Cross Hospital Xining Qinghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,25]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-015-2768-8"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12069"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-014-2418-6"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-025-03728-w"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2018.08.002"},{"issue":"14","key":"e_1_2_12_7_1","article-title":"Acupuncture Compared With Intramuscular Injection of Neostigmine for Postpartum Urinary Retention: A Systematic Review and Meta\u2010Analysis of Randomized Controlled Trials","volume":"5","author":"Xiaomei W.","year":"2018","journal-title":"Evidence\u2010Based Complementary and Alternative Medicine: eCAM"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2018.01.029"},{"issue":"13","key":"e_1_2_12_9_1","article-title":"Acupuncture Therapies for Cancer\u2010Related Fatigue: A Bayesian Network Meta\u2010Analysis and Systematic Review","volume":"27","author":"Hao T.","year":"2023","journal-title":"Frontiers in Oncology"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000035670"},{"issue":"17","key":"e_1_2_12_11_1","first-page":"3197","article-title":"Acupuncture and Related Therapies for Endometriosis: A Network Meta\u2010Analysis of Randomized Controlled Trials","volume":"2","author":"Haiping L.","year":"2024","journal-title":"Journal of Pain Research"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2022.07.060"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.13261"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/luts.12362"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2022.2122800"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2023.101084"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-024-05827-y"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10459-011-9280-9"},{"issue":"3","key":"e_1_2_12_19_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0298438","article-title":"Efficacy of Acupuncture for Anxiety and Depression in Functional Dyspepsia: A Systematic Review and Meta\u2010Analysis","volume":"19","author":"Zhiwei X.","year":"2024","journal-title":"PLoS One"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnss.2020.09.002"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-017-3457-6"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0000000000001099"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2017.26.9.S22"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-021-05074-5"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/NCQ.0000000000000087"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000025683"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-024-05804-5"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2018.01.029"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.3233\/THC-220660"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.25854"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v12.i21.4527"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20926"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0000000000000053"},{"issue":"12","key":"e_1_2_12_34_1","first-page":"1071","article-title":"[Clinical Observation on Deep\u2010Oblique Acupuncture With Long Needle at Guanyuan (CV 4) for Urinary Retention]","volume":"33","author":"Fu Y. Q.","year":"2013","journal-title":"Zhongguo Zhen Jiu Chinese Acupuncture Moxibustion"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000261"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2018.01.029"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2012.10.002"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.70253","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/nau.70253","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.70253","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T03:20:30Z","timestamp":1778815230000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.70253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,25]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/nau.70253"],"URL":"https:\/\/doi.org\/10.1002\/nau.70253","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,25]]},"assertion":[{"value":"2025-10-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}