{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T10:43:44Z","timestamp":1785926624495,"version":"3.56.0"},"reference-count":48,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Both psoriasis and overactive bladder (OAB) are considered systemic conditions that share many inflammatory or immune pathways in the pathogenesis. One previous study found patients with psoriatic arthritis (PsA) reported significantly higher bladder autonomic dysfunction scores compared to controls. But it is currently unclear whether there is an association between psoriasis and OAB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the association between psoriasis and OAB among US population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross\u2010sectional, population\u2010based study utilized representative data of US adults aged 20 \u201359 years from the National Health and Nutrition Examination Survey (NHANES) 2005\u20132006 and 2009\u20132014 cycles. The Overactive Bladder Symptom Score (OABSS) was used to define OAB and group its severity into none, mild, moderate, and severe. Weighted logistic regression models were constructed to investigate the association between psoriasis with OAB or OAB severity. Subgroup analyses were performed to identify whether certain factors could influence the relationship. Sensitivity analyses were further conducted to assess the robustness of our findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 11,643 participants, 50.95% were male and the mean age at recruitment was 39.67 (11.55) years. The prevalence of psoriasis increased with OAB severity (2.34% [none], 3.01% [mild], 5.13% [moderate], 5.33% [severe];\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0008). In weighted logistic regression models, psoriasis was significantly associated with OAB (OR\u2009=\u20091.88, 95% CI: 1.32\u20132.68) after adjusting all covariates, as well as the severity of OAB. Subgroup analyses indicated that the association was stronger among younger participants, males, participants with obesity or hypertension, and those without diabetes or cardiovascular disease (CVD); conversely, no significant associations were observed in participants with pre\u2010diabetes, diabetic mellitus, or CVD. Sensitivity analyses confirmed the robustness of these findings.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study demonstrates a significant association between psoriasis and OAB, with a positive correlation to OAB severity, underscoring the need for early identification and management of OAB symptoms in psoriasis patients to improve overall patient outcomes and enhance their quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nau.70402","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T09:47:08Z","timestamp":1785923228000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Psoriasis and Overactive Bladder Among US Adults: A Study Based on 2005\u20132006 and 2009\u20132014 National Health and Nutrition Examination Survey"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6088-5915","authenticated-orcid":false,"given":"Xiaoxue","family":"Zhuo","sequence":"first","affiliation":[{"name":"Department of Dermatology, West China Hospital Sichuan University Chengdu Sichuan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangyi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, West China Hospital Sichuan University Chengdu Sichuan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4291-7776","authenticated-orcid":false,"given":"Xiaoyan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition The First Affiliated Hospital of Chengdu Medical College Chengdu Sichuan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9259-8083","authenticated-orcid":false,"given":"Pengfei","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, West China Hospital Sichuan University Chengdu Sichuan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,5]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.4006"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.02.1099"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.06.038"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.184"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2013.08.013"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2022.1609"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18044"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2022.01.045"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2006.09.019"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-66758-8"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/luts.12193"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22295"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.04.026"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00013-09"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.02.038"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-022-05110-7"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58020243"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2749"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.03.133"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2024.1345866"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.18-0183"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2024.04.030"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.2145"},{"issue":"1","key":"e_1_2_12_25_1","first-page":"S14","article-title":"Association. AD. 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes\u20102020","volume":"43","year":"2020","journal-title":"Diabetes Care"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.7326\/M20-1340"},{"issue":"17","key":"e_1_2_12_27_1","first-page":"e426","article-title":"2017 ACC\/AHA\/AAPA\/ABC\/ACPM\/AGS\/APhA\/ASH\/ASPC\/NMA\/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines","volume":"138","author":"Whelton P. K.","year":"2018","journal-title":"Circulation"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2021.120652"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.15281"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwn164"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2010.09993.x"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-62842-1"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2024.1386639"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08809.x"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo11110778"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.14171"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-021-00809-4"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00580.2015"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-018-8702-3"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-012-8307-1"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00184-7"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.07.004"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16239"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.118.312246"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.21191"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1113\/JP277452"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192644"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-63448-3"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1368727"}],"container-title":["Neurourology and Urodynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.70402","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/nau.70402","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nau.70402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T09:47:09Z","timestamp":1785923229000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nau.70402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,5]]},"references-count":48,"alternative-id":["10.1002\/nau.70402"],"URL":"https:\/\/doi.org\/10.1002\/nau.70402","archive":["Portico"],"relation":{},"ISSN":["0733-2467","1520-6777"],"issn-type":[{"value":"0733-2467","type":"print"},{"value":"1520-6777","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,5]]},"assertion":[{"value":"2026-02-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"nau.70402"}}