{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T10:30:19Z","timestamp":1786357819641,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurourology and Urodynamics"],"abstract":"ABSTRACT<\/jats:title>\n \n Purpose<\/jats:title>\n Caffeine restriction is frequently recommended in men with lower urinary tract symptoms (LUTS), although evidence regarding its acute effects on objective voiding parameters is limited. We evaluated the short\u2010term impact of single\u2010dose caffeine intake on uroflowmetric outcomes.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n \n In this retrospective study, 156 men with LUTS underwent paired uroflowmetry measurements under standardized conditions before and 60\u2009min after ingestion of 200\u2009mL filtered coffee containing 100\u2009mg caffeine. Maximum urinary flow rate (\n Q<\/jats:italic>\n max<\/jats:sub>\n ), mean flow rate (\n Q<\/jats:italic>\n mean<\/jats:sub>\n ), and post\u2010void residual (PVR) volume were assessed. Subgroup analyses were performed according to baseline\n Q<\/jats:italic>\n max<\/jats:sub>\n , prostate volume, body mass index, and symptom severity. A separate group of 127 patients undergoing repeated uroflowmetry without caffeine exposure was analyzed to assess measurement variability.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Mean\n Q<\/jats:italic>\n max<\/jats:sub>\n increased from 16.12 to 18.33\u2009mL\/s (mean difference 2.21\u2009mL\/s;\n p<\/jats:italic>\n \u2009=\u20090.010; Cohen's\n d<\/jats:italic>\n \u2009=\u20090.33).\n Q<\/jats:italic>\n mean<\/jats:sub>\n increased significantly (\n p<\/jats:italic>\n \u2009=\u20090.003), while PVR remained unchanged. A clinically meaningful improvement (\u0394\n Q<\/jats:italic>\n max<\/jats:sub>\n \u2009\u2265\u20093\u2009mL\/s) occurred in 34.8% of patients. Greater improvement was observed in patients with baseline\n Q<\/jats:italic>\n max<\/jats:sub>\n \u2009\u2265\u200910\u2009mL\/s (\n p<\/jats:italic>\n \u2009=\u20090.036). No significant differences were detected according to prostate volume or obesity status.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Acute caffeine intake resulted in a small but significant increase in urinary flow without worsening residual urine. These findings suggest that short\u2010term caffeine exposure does not adversely affect objective voiding dynamics in men with LUTS.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/nau.70409","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T09:45:58Z","timestamp":1786355158000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Acute Effect of Daily Caffeine Intake on Urination Parameters in Men With Lower Urinary Tract Symptoms"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9894-9489","authenticated-orcid":false,"given":"Yunus Erol","family":"Bozkurt","sequence":"first","affiliation":[{"name":"Department of Urology Manisa City Hospital Manisa T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1985-9312","authenticated-orcid":false,"given":"Mehmet O\u011fuz","family":"\u015eahin","sequence":"additional","affiliation":[{"name":"Department of Urology Manisa City Hospital Manisa T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6870-3824","authenticated-orcid":false,"given":"Mehmet \u015eirin","family":"Ertek","sequence":"additional","affiliation":[{"name":"Department of Urology Manisa City Hospital Manisa T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3208-3547","authenticated-orcid":false,"given":"Bilali Habe\u015f","family":"G\u00fcm\u00fc\u015f","sequence":"additional","affiliation":[{"name":"Department of Urology Manisa City Hospital Manisa 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