{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T14:18:47Z","timestamp":1791209927679,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,9,25]],"date-time":"2007-09-25T00:00:00Z","timestamp":1190678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NMR in Biomedicine"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this work was to use intravoxel incoherent motion (IVIM) to provide a non\u2010invasive <jats:italic>in vivo<\/jats:italic> assessment of the function of the maternal spiral arteries that feed the placenta in normal pregnancy and in pre\u2010eclampsia. Eleven normal pregnant women were scanned at 16, 22, 29 and 35 weeks gestation in a longitudinal study. Nine normal pregnant women and six women with pre\u2010eclampsia were scanned in a cross\u2010sectional study, within 10 days of delivery. The MRI IVIM technique was used to measure the moving blood fraction (f%) at the basal plate. There was no evidence that f% changed with gestational age (P\u2009=\u20090.84), but considering the cross\u2010sectional groups, f% in women with pre\u2010eclampsia was reduced compared with normal pregnancy (mean\u2009\u00b1\u2009SD: 36\u2009\u00b1\u20095% and 27\u2009\u00b1\u20095%; P\u2009&lt;\u20090.005). In conclusion, pregnancies complicated by pre\u2010eclampsia exhibit a reduced fraction of moving blood within the region of the spiral arteries. IVIM performed in the mid\u2010trimester may provide an early means of predicting those pregnancies with an increased likelihood of being complicated by pre\u2010eclampsia. Copyright \u00a9 2007 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/nbm.1199","type":"journal-article","created":{"date-parts":[[2007,9,25]],"date-time":"2007-09-25T06:55:43Z","timestamp":1190703343000},"page":"376-380","source":"Crossref","is-referenced-by-count":41,"title":["Spiral artery blood volume in normal pregnancies and those compromised by pre\u2010eclampsia"],"prefix":"10.1002","volume":"21","author":[{"given":"Rachel J.","family":"Moore","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen S.","family":"Ong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damian J.","family":"Tyler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Duckett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip N.","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Dunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian R.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penny A.","family":"Gowland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,9,25]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/beog.2000.0116"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-4199-5"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.301.6746.259"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-63-755-833"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1995.tb09023.x"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.211.3.r99jn20609"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0730-725X(97)00281-6"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910400318"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)07089-X"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199101000-00002"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2594(200002)43:2<295::AID-MRM18>3.0.CO;2-2"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1053\/plac.2000.0567"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1993.tb12977.x"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.312.7043.1421d"},{"key":"e_1_2_1_16_2","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0002-9378(13)70275-8","article-title":"A 3\u2010year follow\u2010up of children imaged in utero using echo\u2010planar magnetic resonance","volume":"170","author":"Baker PN","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.71.845.9691901"},{"key":"e_1_2_1_18_2","first-page":"110A","article-title":"The structure of myometrial arteries is altered in women with pre\u2010eclampsia","volume":"1","author":"Ong S","year":"2002","journal-title":"J Soc Gynecol Investig"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2594(200102)45:2<247::AID-MRM1033>3.0.CO;2-M"}],"container-title":["NMR in Biomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fnbm.1199","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nbm.1199","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:43:27Z","timestamp":1760949807000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/nbm.1199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9,25]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1002\/nbm.1199"],"URL":"https:\/\/doi.org\/10.1002\/nbm.1199","archive":["Portico"],"relation":{},"ISSN":["0952-3480","1099-1492"],"issn-type":[{"value":"0952-3480","type":"print"},{"value":"1099-1492","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9,25]]}}}