{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:16:36Z","timestamp":1761059796847,"version":"build-2065373602"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T00:00:00Z","timestamp":1410480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003958","name":"Dutch Technology Foundation","doi-asserted-by":"crossref","award":["STW-NIG-10882"],"award-info":[{"award-number":["STW-NIG-10882"]}],"id":[{"id":"10.13039\/501100003958","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NMR in Biomedicine"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:p>Spectral degradations as a result of temporal field variations are observed in MRSI of the human prostate. Moving organs generate substantial temporal and spatial field fluctuations as a result of susceptibility mismatch with the surrounding tissue (i.e. periodic breathing, cardiac motion or random bowel motion). Nine patients with prostate cancer were scanned with an endorectal coil (ERC) on a 7\u2010T MR scanner. Temporal <jats:italic>B<\/jats:italic><jats:sub>0<\/jats:sub> field variations were observed with fast dynamic <jats:italic>B<\/jats:italic><jats:sub>0<\/jats:sub> mapping in these patients. Simulations of dynamic <jats:italic>B<\/jats:italic><jats:sub>0<\/jats:sub> corrections were performed using zero\u2010 to second\u2010order shim terms. In addition, the temporal <jats:italic>B<\/jats:italic><jats:sub>0<\/jats:sub> variations were applied to simulated MR spectra causing, on average, 15% underestimation of the choline\/citrate ratio. Linewidth distortions and frequency shifts (up to 30 and 8\u2009Hz, respectively) were observed. To demonstrate the concept of observing local field fluctuations in real time during MRSI data acquisition, a field probe (FP) tuned and matched for the <jats:sup>19<\/jats:sup>\u2009F frequency was incorporated into the housing of the ERC. The data acquired with the FP were compared with the <jats:italic>B<\/jats:italic><jats:sub>0<\/jats:sub> field map data and used to correct the MRSI datasets retrospectively. The dynamic <jats:italic>B<\/jats:italic><jats:sub>0<\/jats:sub> mapping data showed variations of up to 30\u2009Hz (0.1\u2009ppm) over 72\u2009s at 7\u2009T. The simulated zero\u2010order corrections, calculated as the root mean square, reduced the standard deviation (SD) of the dynamic variations by an average of 41%. When using second\u2010order corrections, the reduction in the SD was, on average, 56%. The FP data showed the same variation range as the dynamic <jats:italic>B<\/jats:italic><jats:sub>0<\/jats:sub> data and the variation patterns corresponded. After retrospective correction, the MRSI data showed artifact reduction and improved spectral resolution. <jats:italic>B<\/jats:italic><jats:sub>0<\/jats:sub> variations can degrade the MRSI substantially. The simple incorporation of an FP into an ERC can improve prostate cancer MRSI without prior knowledge of the origin of the dynamic field distortions. Copyright \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/nbm.3197","type":"journal-article","created":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T05:24:29Z","timestamp":1410499469000},"page":"1353-1360","source":"Crossref","is-referenced-by-count":5,"title":["Temporal <i>B<\/i><sub>0<\/sub> field variation effects on MRSI of the human prostate at 7\u2009T and feasibility of correction using an internal field probe"],"prefix":"10.1002","volume":"27","author":[{"given":"C. S.","family":"Arteaga de Castro","sequence":"first","affiliation":[{"name":"University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. O.","family":"Boer","sequence":"additional","affiliation":[{"name":"University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. P.","family":"Luttje","sequence":"additional","affiliation":[{"name":"University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. 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J.","family":"Klomp","sequence":"additional","affiliation":[{"name":"University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2412051866"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.05.2198"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1723"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1592"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2452062201"},{"issue":"3","key":"e_1_2_8_7_1","first-page":"153","article-title":"Proton MR spectroscopy of prostatic tissue focused on the detection of spermine, a possible biomarker of malignant behavior in prostate cancer","volume":"10","author":"Graaf M","year":"2000","journal-title":"Magn. Reson. Mater. Phys. Biol. 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