{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:27:05Z","timestamp":1790634425181,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,10,7]],"date-time":"2015-10-07T00:00:00Z","timestamp":1444176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NMR in Biomedicine"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:p>The design and construction of a dedicated RF coil setup for human brain imaging (<jats:sup>1<\/jats:sup>H) and spectroscopy (<jats:sup>31<\/jats:sup>P) at ultra\u2010high magnetic field strength (7\u2009T) is presented. The setup is optimized for signal handling at the resonance frequencies for <jats:sup>1<\/jats:sup>H (297.2\u2009MHz) and <jats:sup>31<\/jats:sup>P (120.3\u2009MHz). It consists of an eight\u2010channel <jats:sup>1<\/jats:sup>H transmit\u2013receive head coil with multi\u2010transmit capabilities, and an insertable, actively detunable <jats:sup>31<\/jats:sup>P birdcage (transmit\u2013receive and transmit only), which can be combined with a seven\u2010channel receive\u2010only <jats:sup>31<\/jats:sup>P array. The setup enables anatomical imaging and <jats:sup>31<\/jats:sup>P studies without removal of the coil or the patient. By separating transmit and receive channels and by optimized addition of array signals with whitened singular value decomposition we can obtain a sevenfold increase in SNR of <jats:sup>31<\/jats:sup>P signals in the occipital lobe of the human brain compared with the birdcage alone. These signals can be further enhanced by 30\u2009\u00b1\u20099% using the nuclear Overhauser effect by <jats:italic>B<\/jats:italic><jats:sub>1<\/jats:sub>\u2010shimmed low\u2010power irradiation of water protons. Together, these features enable acquisition of <jats:sup>31<\/jats:sup>P MRSI at high spatial resolutions (3.0\u2009cm<jats:sup>3<\/jats:sup>\u2009voxel) in the occipital lobe of the human brain in clinically acceptable scan times (~15\u2009min). \u00a9 2015 The Authors. NMR in Biomedicine published by John Wiley &amp; Sons Ltd.<\/jats:p>","DOI":"10.1002\/nbm.3422","type":"journal-article","created":{"date-parts":[[2015,10,7]],"date-time":"2015-10-07T08:02:49Z","timestamp":1444204969000},"page":"1570-1578","source":"Crossref","is-referenced-by-count":24,"title":["Optimized <sup>31<\/sup>P MRS in the human brain at 7\u2009T with a dedicated RF coil setup"],"prefix":"10.1002","volume":"28","author":[{"given":"Bart L.","family":"van de Bank","sequence":"first","affiliation":[{"name":"Department of Radiology and Nuclear Medicine Radboud University Medical Center  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Orzada","sequence":"additional","affiliation":[{"name":"Erwin L. 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