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In this work, we present a local temperature correlation matrix formalism and apply it to impose strict constraints on maximum absolute temperature in pTx RF pulse design for head and hip regions. Electromagnetic field simulations were performed on the head and hip of virtual body models. Temperature correlation matrices were calculated for four different exposure durations ranging between 6 and 24\u00a0min using simulated fields and body\u2010specific constants. Parallel transmission RF pulses were designed using either SAR or temperature constraints, and compared with each other and unconstrained RF pulse design in terms of excitation fidelity and safety. The use of temperature correlation matrices resulted in better excitation fidelity compared with the use of SAR in parallel transmission RF pulse design (for the 6\u00a0min exposure period, 8.8% versus 21.0% for the head and 28.0% versus 32.2% for the hip region). As RF exposure duration increases (from 6\u00a0min to 24\u00a0min), the benefit of using temperature correlation matrices on RF pulse design diminishes. However, the safety of the subject is always guaranteed (the maximum temperature was equal to 39\u00b0C). This trend was observed in both head and hip regions, where the perfusion rates are very different.<\/jats:p>","DOI":"10.1002\/nbm.3694","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T12:06:47Z","timestamp":1486728407000},"source":"Crossref","is-referenced-by-count":9,"title":["Parallel transmission RF pulse design with strict temperature constraints"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8809-5945","authenticated-orcid":false,"given":"Cem M.","family":"Deniz","sequence":"first","affiliation":[{"name":"Center for Advanced Imaging Innovation and Research (CAI2R) New York University School of Medicine  New York NY USA"},{"name":"Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology New York University School of Medicine  New York NY USA"},{"name":"The Sackler Institute of Graduate Biomedical Sciences New York University School of Medicine  New York NY USA"},{"name":"NYU WIRELESS New York University Tandon School of Engineering  Brooklyn NY USA"},{"name":"RF Test Labs, Inc.  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