{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:01:26Z","timestamp":1791874886235,"version":"4.3.4"},"reference-count":45,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T00:00:00Z","timestamp":1722384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["K01\u2010AG075178\u201001"],"award-info":[{"award-number":["K01\u2010AG075178\u201001"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003653","name":"Korea National Institute of Health","doi-asserted-by":"publisher","award":["R01\u2010CA202911"],"award-info":[{"award-number":["R01\u2010CA202911"]}],"id":[{"id":"10.13039\/501100003653","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["NMR in Biomedicine"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We aim to assess a straightforward technique to enhance spectral quality in the brain, particularly in the cerebellum, during 7\u2009T MRI scans. This is achieved through a wireless RF array insert designed to mitigate signal dropouts caused by the limited transmit field efficiency in the inferior part of the brain. We recently developed a wireless RF array to improve MRI and <jats:sup>1<\/jats:sup>H\u2010MRS at 7\u2009T by augmenting signal via inductive coupling between the wireless RF array and the MRI coil. In vivo experiments on a Siemens 7\u2009T whole\u2010body human scanner with a Nova 1Tx\/32Rx head coil quantified the impact of the dorsal cervical array in improving signal in the posterior fossa, including the cerebellum, where the transmit efficiency of the coil is inherently low. The <jats:sup>1<\/jats:sup>H\u2010MRS experimental protocol consisted of paired acquisition of data sets, both with and without the RF array, using the semi\u2010LASER and SASSI sequences. The overall results indicate that the localized <jats:sup>1<\/jats:sup>H\u2010MRS is improved significantly in the presence of the array. Comparison of in vivo <jats:sup>1<\/jats:sup>H\u2010MRS plots in the presence versus absence of the array demonstrated an average SNR enhancement of a factor of 2.2. LCModel analysis reported reduced Cram\u00e9r\u2013Rao lower bounds, indicating more confident fits. This wireless RF array can significantly increase detection sensitivity. It may reduce the RF transmission power and data acquisition time for <jats:sup>1<\/jats:sup>H\u2010MRS and MRI applications, specifically at 7\u2009T, where <jats:sup>1<\/jats:sup>H\u2010MRS requires a high\u2010power RF pulse. The array could provide a cost\u2010effective and efficient solution to improve detection sensitivity for human <jats:sup>1<\/jats:sup>H\u2010MRS and MRI in the regions with lower transmit efficiency.<\/jats:p>","DOI":"10.1002\/nbm.5224","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T07:26:06Z","timestamp":1722410766000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Improvement of MRS at ultra\u2010high field using a wireless RF array"],"prefix":"10.1002","volume":"37","author":[{"given":"Andrew","family":"Frankini","sequence":"first","affiliation":[{"name":"Department of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII) Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII) Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7877-4813","authenticated-orcid":false,"given":"Alan C.","family":"Seifert","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII) Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley N.","family":"Delman","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII) Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varun","family":"Subramaniam","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII) Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priti","family":"Balchandani","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII) Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akbar","family":"Alipour","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Molecular and Interventional Radiology, BioMedical Engineering and Imaging Institute (BMEII) Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2015.10.006"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073197"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.11.031"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2021.01.004"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24672"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2009.06.008"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20101\u201061737\u2010992\u20105_9"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnmrs.2006.06.002"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-008045046-9.00300-4"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1156"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21067"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.22086"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nic.2012.10.003"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910230209"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.2903"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0730\u2010725x(02)00483\u20106"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmr.2003.11.003"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28614"},{"key":"e_1_2_9_20_1","volume-title":"Discovering the Brain","author":"Ackerman S","year":"1992"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.16.3.367"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2023.1108339"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2015.00066"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2013.05.029"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20011"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1049"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20603"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010017\u201001932\u20109"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0183562"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.23089"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/RMR.0000000000000204"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.5094"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnmrs.2018.06.001"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201002533\u20103"},{"key":"e_1_2_9_35_1","unstructured":"AlipourA SeifertAC DelmanBN et al.Enhanced ultra\u2010high field brain MRI using a wireless radiofrequency sheet. Presented at: 2021 ISMRM & ISMRT Annual Meeting & Exhibition; May 2021; online."},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1109\/tmi.2008.2006523"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.698"},{"key":"e_1_2_9_38_1","unstructured":"Standard Test Method for Measurement of Radio Frequency Induced Heating On or Near Passive Implants During Magnetic Resonance Imaging. ASTM F2182\u201011a 2011.10.1520\/F2182\u201011A"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1727"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.22473"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.26025"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2223\u20104292.2015.03.05"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1638"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21961"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099\u20101492(199712)10:8%3C394::AID\u2010NBM494%3E3.0.CO;2%5F0"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1423"}],"container-title":["NMR in Biomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nbm.5224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:16:53Z","timestamp":1760966213000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/nbm.5224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,31]]},"references-count":45,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/nbm.5224"],"URL":"https:\/\/doi.org\/10.1002\/nbm.5224","archive":["Portico"],"relation":{},"ISSN":["0952-3480","1099-1492"],"issn-type":[{"value":"0952-3480","type":"print"},{"value":"1099-1492","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,31]]},"assertion":[{"value":"2024-01-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e5224"}}