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These substances are essential for a healthy brain, and their abnormalities are often related to various neurological disorders. Recently, an advanced susceptibility mapping technique, which is referred to as\n                    <jats:italic>\u03c7<\/jats:italic>\n                    \u2010separation (pronounced as \u201cchi\u201d\u2010separation), has been proposed, successfully disentangling paramagnetic iron from diamagnetic myelin. This method provided a new opportunity for generating high\u2010resolution iron and myelin maps of the brain. Utilizing this technique, this study constructs a normative\n                    <jats:italic>\u03c7<\/jats:italic>\n                    \u2010separation atlas from 106 healthy human brains. The resulting atlas provides detailed anatomical structures associated with the distributions of iron and myelin, clearly delineating subcortical nuclei, thalamic nuclei, and white matter fiber bundles. Additionally, susceptibility values in a number of regions of interest are reported along with age\u2010dependent changes. This atlas may have direct applications such as localization of subcortical structures for deep brain stimulation or high\u2010intensity focused ultrasound and also serve as a valuable resource for future research.\n                  <\/jats:p>","DOI":"10.1002\/nbm.5226","type":"journal-article","created":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T07:38:30Z","timestamp":1724139510000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["A human brain atlas of\n                    <i>\u03c7<\/i>\n                    \u2010separation for normative iron and myelin distributions"],"prefix":"10.1002","volume":"37","author":[{"given":"Kyeongseon","family":"Min","sequence":"first","affiliation":[{"name":"Department of Electrical and Computer Engineering Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beomseok","family":"Sohn","sequence":"additional","affiliation":[{"name":"Department of Radiology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woo Jung","family":"Kim","sequence":"additional","affiliation":[{"name":"Institute of Behavioral Sciences in Medicine Yonsei University College of Medicine  Seoul Republic of Korea"},{"name":"Department of Psychiatry, Yongin Severance Hospital Yonsei University College of Medicine  Yongin Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chae Jung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Radiology, Yongin Severance Hospital Yonsei University College of Medicine  Yongin Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soohwa","family":"Song","sequence":"additional","affiliation":[{"name":"Heuron Co., Ltd  Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Hoon","family":"Shin","sequence":"additional","affiliation":[{"name":"Heuron Co., Ltd  Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung Won","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Severance Hospital Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na\u2010Young","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Radiology, Severance Hospital Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minjun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Electrical and Computer Engineering Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeong\u2010Geol","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Radiology Johns Hopkins University School of Medicine  Baltimore Maryland USA"},{"name":"F. 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