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A novel single scan 3D imaging method, incorporating Wave\u2010CAIPI and MULTIPLEX technologies and named WAMP, has been developed for rapid and comprehensive parametric imaging in clinical diagnostic applications. Featuring a hybrid design that includes wave encoding, the CAIPIRINHA sampling pattern, dual time of repetition (TR), dual flip angle (FA), multiecho, and optional flow modulation, the WAMP method captures information on RF B1t fields, proton density (PD), T1, susceptibility, and blood flow. This method facilitates the synthesis of multiple qualitative contrast\u2010weighted images and relaxometric parametric maps. A single WAMP scan generates multiple contrast\u2010weighted images and relaxometric parametric maps, including PD\u2010weighted (PDW), T1\u2010weighted (T1W), T2*\u2010weighted (T2W), adjusted T1\u2010weighted (aT1W), susceptibility\u2010weighted imaging (SWI), B1t map, T1 map, T2\/R2* map, PD map, and quantitative susceptibility mapping (QSM). 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