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However, interpreting an MRI scan requires an exceptional amount of skill because abnormalities on scans are frequently inconsistent with clinical symptoms, making it difficult to convert the findings into effective treatment strategies. Furthermore, MRI is an expensive process, and its frequent utilization to monitor an illness increases healthcare costs. To overcome these drawbacks, this research employs advanced technological approaches to develop a deep learning system for classifying types of MS through clinical brain MRI scans. The major innovation of this model is to influence the convolution network with attention concept and recurrent\u2010based deep learning for classifying the disorder; this also proposes an optimization algorithm for tuning the parameter to enhance the performance. Initially, the total images as 3427 are collected from database, in which the collected samples are categorized for training and testing phase. Here, the segmentation is carried out by adaptive and attentive\u2010based mask regional convolution neural network (AA\u2010MRCNN). In this phase, the MRCNN's parameters are finely tuned with an enhanced pine cone optimization algorithm (EPCOA) to guarantee outstanding efficiency. Further, the segmented image is given to recurrent MobileNet with long short term memory (RM\u2010LSTM) for getting the classification outcomes. Through experimental analysis, this deep learning model is acquired 95.4% for accuracy, 95.3% for sensitivity, and 95.4% for specificity. Hence, these results prove that it has high potential for appropriately classifying the sclerosis disorder.<\/jats:p>","DOI":"10.1002\/nbm.70036","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:21:00Z","timestamp":1745464860000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["An Intelligent Model of Segmentation and Classification Using Enhanced Optimization\u2010Based Attentive Mask RCNN and Recurrent MobileNet With LSTM for Multiple Sclerosis Types With Clinical Brain MRI"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2960-9530","authenticated-orcid":false,"given":"G.","family":"Gopichand","sequence":"first","affiliation":[{"name":"School of Computer Science and Engineering Vellore Institute of Technology  Vellore Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kovvuri\u00a0N.","family":"Bhargavi","sequence":"additional","affiliation":[{"name":"Department of CSE Aditya University  Surampalem Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.\u00a0V.\u00a0S.","family":"Ramprasad","sequence":"additional","affiliation":[{"name":"Department of EECE GITAM (Deemed to be University)  Visakhapatnam Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep\u00a0Vinaik","family":"Kodavanti","sequence":"additional","affiliation":[{"name":"EECE Department GITAM (Deemed to be University)  Visakhapatnam Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Padmavathi","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Engineering Swarna Bharathi Institute of Science &amp; Technology  Khammam India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1109\/TCYB.2019.2933633"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2014.2322280"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1109\/JBHI.2022.3225475"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1109\/JBHI.2014.2308279"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2021.3137280"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2022.3225528"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2019.2935060"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1109\/JBHI.2015.2439242"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2011.2173766"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2022.3192309"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2016.2548501"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1109\/TCYB.2018.2797905"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1109\/TFUZZ.2019.2930478"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2022.3174827"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2006.883453"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1109\/TCYB.2019.2952937"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2022.3218720"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1049\/iet-ipr.2020.1128"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0000000000000854"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2019191061"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.51037"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2021.109098"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2023.104516"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415\u2010023\u201011778\u2010z"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suscom.2022.100706"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1109\/ACCESS.2023.3260982"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1109\/TITB.2010.2091279"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2014.2382561"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2022.105402"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1109\/TFUZZ.2024.3369944"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.908143"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.981019"},{"key":"e_1_2_10_34_1","doi-asserted-by":"crossref","unstructured":"S.Solanki S. 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