{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T06:55:57Z","timestamp":1776322557810,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T00:00:00Z","timestamp":1774137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T00:00:00Z","timestamp":1774137600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["NMR in Biomedicine"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The goal of this work was to evaluate the impact of gadolinium on quantitative myelin MRI metrics in ex\u00a0vivo tissue. Ex\u00a0vivo ferret spinal cords were imaged with and without gadolinium. Mean metrics were calculated across white and gray matter. T\n                    <jats:sub>1<\/jats:sub>\n                    of the free proton pool and T\n                    <jats:sub>2<\/jats:sub>\n                    of water other than myelin showed the largest differences between gadolinium and without gadolinium samples. Myelin water fraction, bound pool fraction, and myelin water T\n                    <jats:sub>2<\/jats:sub>\n                    showed a 2%\u201312% change between gadolinium and no gadolinium data. The relationships between the myelin water fraction, bound pool fraction, and myelin water T\n                    <jats:sub>2<\/jats:sub>\n                    and a recently established axon diameter surrogate were not affected by gadolinium; however, the trends observed between T\n                    <jats:sub>1<\/jats:sub>\n                    of the free proton pool and other water T\n                    <jats:sub>2<\/jats:sub>\n                    and the axon diameter surrogate without gadolinium were flattened in the samples with gadolinium. Overall, the impacts of gadolinium were primarily observed in the relaxation parameters of the non\u2010myelin proton pools.\n                  <\/jats:p>","DOI":"10.1002\/nbm.70275","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T04:36:19Z","timestamp":1774240579000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Gadolinium on Quantitative Myelin Metrics in Ex\u00a0Vivo Spinal Cord"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0408-4831","authenticated-orcid":false,"given":"Hannah\u00a0E.","family":"Alderson","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering Vanderbilt University  Nashville Tennessee USA"},{"name":"Vanderbilt University Institute of Imaging Science  Nashville Tennessee 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