{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T22:33:07Z","timestamp":1788733987772,"version":"build-2803163510"},"reference-count":52,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,5,15]],"date-time":"2018-05-15T00:00:00Z","timestamp":1526342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Parenteral nutrition has significantly and positively affected the clinical care of patients for &gt;50\u00a0years. The 2016 Society of Critical Care Medicine\/American Society for Parenteral and Enteral Nutrition guidelines for the provision of nutrition support to adult patients emphasize the role of this therapy in attenuating the stress response and impacting the immune response, among other benefits. Malnutrition in hospitalized patients remains a major problem; it is underdiagnosed and often undertreated. Malnourished patients are more likely to suffer from infections, pneumonia, and pressure ulcers, among other serious concerns. Enteral nutrition is considered first\u2010line therapy in many of these patients; however, data suggest that many patients receive far less than prescribed amounts for a variety of reasons. Supplemental parenteral nutrition (SPN), used to augment nutrition support of appropriate adult patients and better meet nutrition goals, is not often used in the United States. The purposes of this review are to highlight selected studies in the literature that support and question the use and value of SPN in adult patients; propose consideration of 2 definitions for SPN, \u201cearly\u201d and \u201ctraditional\u201d; and encourage clinicians to consider SPN for appropriate patients.<\/jats:p>","DOI":"10.1002\/ncp.10096","type":"journal-article","created":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T11:46:03Z","timestamp":1527767163000},"page":"359-369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Supplemental Parenteral Nutrition: Review of the Literature and Current Nutrition Guidelines"],"prefix":"10.1002","volume":"33","author":[{"given":"Mary K.","family":"Russell","sequence":"first","affiliation":[{"name":"Senior Manager Medical Affairs Baxter Healthcare Corporation  Deerfield Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul E.","family":"Wischmeyer","sequence":"additional","affiliation":[{"name":"Professor of Anesthesiology and Surgery Associate Vice Chair for Clinical Research Director Perioperative Research at the Duke Clinical Research Institute  Durham North Carolina USA"},{"name":"Director Nutrition and TPN Service Duke University Medical Center and Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,15]]},"reference":[{"issue":"1","key":"e_1_2_8_2_1","first-page":"134","article-title":"Long\u2010term total parenteral nutrition with growth, development, and positive nitrogen balance","volume":"64","author":"Dudrick SJ","year":"1968","journal-title":"Surgery"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607114521833"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607117695251"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2009.04.002"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607112468769"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607115621863"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccc.2016.12.006"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2005.03.006"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2005.10.010"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph8020514"},{"key":"e_1_2_8_12_1","unstructured":"WeissAJ FingarKR BarrettML et\u00a0al.Characteristics of hospital stays involving malnutrition 20131. 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