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Weight loss due to tumor or tumor\u2010related factors remains a major health issue among head and neck cancer patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 357 patients were identified for the study. Possible weight\u2010loss predictors were determined in the patients undergoing RT based on the patient demographics, tumor site, and treatment characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of patients was 52 years, whereas the median age was 51 years (range, 18\u201387). Two hundred and thirteen (66%) patients had oral cavity cancers, 43 (14%) had oropharyngeal cancer, 26 (8%) had hypopharyngeal cancer, 13 (6%) had larynx cancer, and 19 (6%) had other site involvement. A total of 192 patients received 3\u2010dimensional conformal radiation therapy (3DCRT), whereas 127 patients received intensity modulated radiation therapy\u2013image guided radiation therapy (IMRT\u2010IGRT), 212 (66%) received concurrent chemotherapy, and 107 (34%) patients did not receive concurrent chemotherapy. A total of 127 (40%) of the patients gained weight during the first week of RT; on the other hand, maximum weight loss among patients was occurred during the third and fourth weeks of RT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Analysis by logistic regression determined there is significant weight loss (&gt;10%) in patients receiving radical RT as compared with adjuvant RT. Better outcomes were observed in patients receiving RT by IMRT\u2010IGRT technique as compared with 3DCRT technique.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ncp.10488","type":"journal-article","created":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T06:13:47Z","timestamp":1587708827000},"page":"1047-1052","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Predictors of Weight Loss in Patients With Head and Neck Cancer Receiving Radiation or Concurrent Chemoradiation Treated at a Tertiary Cancer Center"],"prefix":"10.1002","volume":"35","author":[{"given":"Prakash","family":"Pandit","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology HCG Manavata Cancer Centre  Nashik Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshankumar","family":"Patil","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology HCG Manavata Cancer Centre  Nashik Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Palwe","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology HCG Manavata Cancer Centre  Nashik Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4288-1120","authenticated-orcid":false,"given":"Venkata Ramesh","family":"Yasam","sequence":"additional","affiliation":[{"name":"Department of Academics HCG Manavata Cancer Centre  Nashik Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajnish","family":"Nagarkar","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology HCG Manavata Cancer Centre  Nashik Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,24]]},"reference":[{"key":"#cr-split#-e_1_2_8_2_1.1","unstructured":"FerlayJ SoerjomataramI ErvikM et al.International Agency for Research on Cancer. 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