{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:10:21Z","timestamp":1791828621708,"version":"4.3.4"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T00:00:00Z","timestamp":1661731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Home enteral nutrition (HEN) is frequently prescribed to individuals who cannot consume adequate food orally. Commercial blenderized enteral formulas (CBEF) containing real\u2010food ingredients are becoming more popular and more widely available; however, the demographics of patients receiving these formulas have rarely been evaluated, and little data are available on patient tolerance in the community.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>US claims data were obtained for children and adolescents\/adults who used the CBEF of interest as the sole source of nutrition via enteral feeding tube in the community setting following discharge from acute care. Demographics, concomitant medications, clinical diagnoses, and Charlson Comorbidity Index scores were tabulated using descriptive statistics. Gastrointestinal (GI) symptoms before and after hospital discharge were compared using significance tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 231 participants (180 children, 51 adolescents\/adults). CBEFs were prescribed to patients with a variety of diagnoses, of which the most common were digestive and respiratory disorders. Children experienced significantly lower rates of diarrhea, nausea, vomiting, constipation, and abdominal distension in the weeks following hospital discharge compared with the baseline (all <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Adolescents\/adults experienced significantly lower rates of constipation, nausea, and vomiting (all <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Neither group increased their usage of GI medications following hospital discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These CBEFs, based on real\u2010food ingredients, were prescribed to diverse patients in the community and were well tolerated. These formulas offer an alternative to standard polymeric formulas and an alternative or adjunct to homemade blenderized formulas.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ncp.10905","type":"journal-article","created":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T05:49:55Z","timestamp":1661752195000},"page":"449-457","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Understanding the use and tolerance of a pediatric and an adult commercial blenderized enteral formula through real\u2010world data"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3050-8633","authenticated-orcid":false,"given":"Cindy","family":"Steel","sequence":"first","affiliation":[{"name":"Nestl\u00e9 Health Science Canada North York Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Wile","sequence":"additional","affiliation":[{"name":"Nestl\u00e9 Health Science Canada North York Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Li","sequence":"additional","affiliation":[{"name":"Clarivate Data Analytics &amp; Insights Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swapna","family":"Yedulla","sequence":"additional","affiliation":[{"name":"Clarivate Data Analytics &amp; Insights Bangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Hare","sequence":"additional","affiliation":[{"name":"Clarivate Data Analytics &amp; Insights Bicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bethany","family":"Hopkins","sequence":"additional","affiliation":[{"name":"Nestl\u00e9 Health Science Canada North York Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10081020"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu7042524"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10649"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0115426506021004411"},{"issue":"1","key":"e_1_2_8_6_1","first-page":"18","article-title":"Evaluating growth and tolerance of blenderized tube feeding formulas in children: a narrative review of the literature","volume":"3","author":"Adams RL","year":"2021","journal-title":"J Food Nutr Sci"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3148\/cjdpr-2019-007"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.2062"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0884533616669703"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10812"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10493"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.3148\/cjdpr-2020-012"},{"key":"e_1_2_8_13_1","unstructured":"Clarivate. 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