{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:41:13Z","timestamp":1784547673184,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T00:00:00Z","timestamp":1667952000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cancer cachexia (CC) is highly prevalent and associated with significant morbidity and mortality, yet underrecognized. In 2011, an international cachexia consensus (ICC) proposed a definition, assessment framework, and stages for classification: cancer precachexia, cachexia, and refractory cachexia. The authors anticipated that a \u201cmore practical classification approach for clinical practice\u201d would be required, which we interpreted as a bedside assessment based on clinical data. We investigated whether the ICC classification could be employed in routine dietetic practice without access to objective muscle mass measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 200 consecutive patients with solid tumors were collected as part of clinical practice by oncology dietitians in five tertiary referral hospitals. Dietitians used information gathered during their routine assessment and applied the ICC framework to assign a stage. When the dietitian was unable to assign a stage, the reason was noted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Based on available data, classification was possible in 177 (88%); 23 (12%) could not be staged. The reasons cited were as follows: unknown C\u2010reactive protein (<jats:italic>n<\/jats:italic>\u2009=\u200914), complex clinical situation (<jats:italic>n<\/jats:italic>\u2009=\u20095), unknown weight loss (<jats:italic>n<\/jats:italic>\u2009=\u20092), and acute illness (<jats:italic>n<\/jats:italic>\u2009=\u20092). Thirty (17%) of the 177 participants were judged to be noncachectic.\u00a0 One hundred twelve (83%) met the criteria for 1 of the 3 ICC stages: 92 (52%) were cachectic; 35 (20%) precachectic, and 20 (11%) refractory.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CC staging based on the ICC classification was feasible and practical in routine dietetic practice even without access to objective muscle mass measures. Once validated and operationalized, expert clinical assessment by a dietitian could be a cost\u2010effective means to identify and stage CC, with more resource\u2010intensive means used when there is clinical doubt.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ncp.10915","type":"journal-article","created":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T19:53:45Z","timestamp":1668023625000},"page":"790-797","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Application of the 2011 international consensus cancer cachexia classification in routine oncology dietetic practice: An observational study"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3631-7563","authenticated-orcid":false,"given":"Aynur","family":"Aktas","sequence":"first","affiliation":[{"name":"Department of Supportive Oncology Levine Cancer Institute, Atrium Health  Charlotte North Carolina 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