{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T20:31:44Z","timestamp":1789677104218,"version":"4.0.1"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,1,8]],"date-time":"2023-01-08T00:00:00Z","timestamp":1673136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Taste and smell abnormalities (TSAs) are present in all cancer stages and may contribute to malnutrition. Despite this, they are rarely screened for. This study examined the prevalence and characteristics of TSAs and their influence on subjective food intake in advanced cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients with advanced cancer were recruited. A modified Taste and Smell Survey assessed subjective TSAs. Objective TSAs were assessed with validated taste strips and \u201cSniffin Sticks.\u201d A six\u2010item food intake questionnaire identified any effect TSAs had on food preferences\/aversions. Nutrition status was evaluated with the abridged Patient\u2010Generated Subjective Global Assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All 30 participants had either subjective or objective TSAs. The prevalence of TSAs varied based on the assessment tool used. Participants were more aware of taste changes (TCs) than smell changes (SCs). TCs caused reduced food intake in 13 participants. Six reported SCs affected food intake. Food choices caused by TSAs were inconsistent. Some foods preferred because of TSAs were avoided by other participants. None received nutrition counseling on TSA management. Almost all were at malnutrition risk (97%). Almost half (47%) felt TSAs reduced quality of life (QoL). Participants reported \u201cnot looking forward to meals\u201d and \u201ccan't sit down and eat anything\u201d because of TSAs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>TSAs were highly prevalent and impactful on food intake. Both TCs and SCs were complex and varied on an individual basis. Despite the effect on health and QoL, no patients received any nutrition counseling on TSA management. Individualized screening and advice are needed for TSAs in advanced cancer.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ncp.10943","type":"journal-article","created":{"date-parts":[[2023,1,8]],"date-time":"2023-01-08T05:38:40Z","timestamp":1673156320000},"page":"807-816","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Taste and smell abnormalities in advanced cancer: Negative impact on subjective food intake"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7757-3865","authenticated-orcid":false,"given":"Aidan","family":"O'Donoghue","sequence":"first","affiliation":[{"name":"School of Medicine Trinity College Dublin Dublin Ireland"},{"name":"Academic Department of Palliative Medicine Our Lady's Hospice &amp; Care Services Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8233-9184","authenticated-orcid":false,"given":"Michelle","family":"Barrett","sequence":"additional","affiliation":[{"name":"Academic Department of Palliative Medicine Our Lady's Hospice &amp; Care Services Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5030-7639","authenticated-orcid":false,"given":"Pauline Ui","family":"Dhuibhir","sequence":"additional","affiliation":[{"name":"Academic Department of Palliative Medicine Our Lady's Hospice &amp; Care Services Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8921-9006","authenticated-orcid":false,"given":"Aileen","family":"Kennedy","sequence":"additional","affiliation":[{"name":"School of Biological and Health Sciences Technological University Dublin Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2310-1248","authenticated-orcid":false,"given":"Norma","family":"O'Leary","sequence":"additional","affiliation":[{"name":"Department of Palliative Medicine St James's Hospital Dublin Ireland"},{"name":"Department of Palliative Medicine Our Lady's Hospice &amp; Care Services Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9310-1729","authenticated-orcid":false,"given":"Declan","family":"Walsh","sequence":"additional","affiliation":[{"name":"Department of Supportive Oncology Levine Cancer Institute Charlotte North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,8]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"National Cancer Registry Ireland.Cancer in Ireland 1994\u20102017 with Estimates for 2017\u20102019: Annual Report of the National Cancer Registry. 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