{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T03:57:10Z","timestamp":1778990230195,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T00:00:00Z","timestamp":1703548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100013238","name":"Faculty of Medicine Siriraj Hospital, Mahidol University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013238","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sarcopenia and frailty are frequently observed in older adult patients and linked to unfavorable postoperative outcomes. Identifying low muscle mass and function is primary for diagnosing sarcopenia. The simpler screening, which excludes muscle mass measurement, exhibited strong predictive capabilities in identifying sarcopenia. This research explored the association between sarcopenia, as defined by the C3 formula, and long\u2010term outcomes in older adult cancer patients who underwent surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Surgical cancer patients aged 60 and older were enrolled. Sarcopenia was identified using the C3 formula, assessing muscle strength through handgrip strength, physical performance via a 6\u2010m walk test, and nutrition status via the Mini Nutritional Assessment\u2013Short Form. Long\u2010term outcomes were evaluated with the Barthel Index for activities of daily living (B\u2010ADL) at 3 months, as well as 1\u2010year mortality rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study enrolled 251 patients, with 130 classified as sarcopenic according to the C3 formula. Compared with nonsarcopenic patients, patients with sarcopenia exhibited a higher frequency of moderate to severe disability (B\u2010ADL \u226470) 3 months postdischarge (19.5% vs 5.2%; <jats:italic>P<\/jats:italic>\u2009=\u20090.001) and elevated 1\u2010year mortality rates (29.5% vs 14.9%; <jats:italic>P<\/jats:italic>\u2009=\u20090.006). No significant differences were observed in infection rates, hospital stay duration, or in\u2010hospital mortality. Distant organ metastasis (HR\u2009=\u20093.99; 95% CI\u2009=\u20092.25\u20137.07) and sarcopenia defined by the C3 formula (HR\u2009=\u20091.78; 95% CI\u2009=\u20091.01\u20133.15) were identified as independent risk factors for 1\u2010year mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The simplified sarcopenia screening tool was associated with increased rates of moderate to severe disability 3 months postdischarge and higher 1\u2010year mortality rates compared with nonsarcopenic patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ncp.11109","type":"journal-article","created":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T07:24:47Z","timestamp":1703575487000},"page":"599-610","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The association between sarcopenia, defined by a simplified screening tool, and long\u2010term outcomes"],"prefix":"10.1002","volume":"39","author":[{"given":"Thassayu","family":"Yuyen","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weerasak","family":"Muangpaisan","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Medicine Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9950-4414","authenticated-orcid":false,"given":"Pornpoj","family":"Pramyothin","sequence":"additional","affiliation":[{"name":"Division of Nutrition, Department of Medicine Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chayanan","family":"Thanakiattiwibun","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5407-306X","authenticated-orcid":false,"given":"Onuma","family":"Chaiwat","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,12,26]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Health Organization. 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