{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:51:34Z","timestamp":1786978294597,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study aimed to determine the prevalence of probable sarcopenia and sarcopenia in patients with inflammatory bowel disease (IBD) by using the European Working Group on Sarcopenia in Older People (EWGSOP2) diagnostic criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sarcopenia was assessed by using the sequential four\u2010step algorithm. (1) Find: Sarcopenia risk by simple clinical symptom index (strength, assistance walking, rise from a chair, climb stairs, and falls [SARC\u2010F questionnaire]). (2) Assess: Probable sarcopenia by low muscle strength on handgrip. (3) Confirm: Confirmed sarcopenia by low appendicular skeletal muscle mass on bioimpedance analysis. (4) Severity: Severe sarcopenia by low 4\u2010m gait speed test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 129 adult patients with IBD younger than 65 years and 50 age\u2010 and sex\u2010matched healthy control (HC) participants were included to the study. Handgrip strength, gait speed, and SARC\u2010F scores were significantly lower in patients with IBD than in the HCs (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.032, &lt;0.0001, and &lt;0.0001, respectively). Based on the EWGSOP2 definition, 17.8% of patients with IBD had probable sarcopenia, and six patients had confirmed sarcopenia. According to the ethnicity\u2010based population thresholds, 34.9% of patients with IBD had probable sarcopenia, and two patients had confirmed sarcopenia. Corticosteroid use within the past year was identified as an independent risk factor for low muscle strength (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.012; odds ratio, 4.133), along with advanced age and disease activity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>One\u2010third of the patients younger than 65 years with IBD had probable sarcopenia, defined as low muscle strength, whereas the incidence of confirmed sarcopenia remained relatively low.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ncp.11125","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T04:56:27Z","timestamp":1707281787000},"page":"557-567","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["High prevalence of muscle weakness and probable sarcopenia in patients with inflammatory bowel disease"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1539-501X","authenticated-orcid":false,"given":"Ilkay","family":"Ergenc","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, School of Medicine Marmara University Pendik \u0130stanbul Turkey"},{"name":"Department of Hepatology King's College Hospital NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8684-2641","authenticated-orcid":false,"given":"Chasan","family":"Ismail Basa","sequence":"additional","affiliation":[{"name":"School of Medicine Marmara University \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9474-4419","authenticated-orcid":false,"given":"Alper","family":"Uzum","sequence":"additional","affiliation":[{"name":"School of Medicine Marmara University 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