{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T19:08:29Z","timestamp":1770750509955,"version":"3.50.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Intestinal failure (IF) describes a condition of insufficient absorption capacity and general function of the gastrointestinal tract and may necessitate long\u2010term intravenous fluid and nutrient supplementation. Quality of life (QoL) may be reduced in these patients. The aim of the study was to analyze QoL by two tools (SBS\u2010QoL and SF\u201012) to elucidate which parameters impact QoL in patients with IF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>QoL was assessed in a cohort of 105 patients with IF at a tertiary referral center for intestinal rehabilitation. Complete data for SBS\u2010QoL and SF\u201012 were available in 44 of 81 surviving patients at a single time point for a cross\u2010sectional analysis. Medical data, outcome parameters, and comorbidities (Charlson comorbidity index [CCI]) were extracted and entered in a prospective database for analysis and correlation with QoL assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Subscales of SBS\u2010QoL and SF\u201012 highly correlated with each other (<jats:italic>P<\/jats:italic>\u2009=\u2009\u22120.64 for physical subscales; <jats:italic>P<\/jats:italic>\u2009=\u2009\u22120.75 for mental subscales). Significant differences in QoL were detected in patients with Messing Type I (end\u2010jejunostomy) and Type III anatomy (ileocolonic anastomosis) (one\u2010way ANOVA: <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Performance of autologous gut reconstruction (AGR) was associated with significantly better physical QoL. CCI correlated significantly with QoL scores. Longer duration of illness resulted in higher QoL in SBS\u2010QoL (reduction of 0.15 per month; <jats:italic>P<\/jats:italic>\u2009=\u20090.045).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both SBS\u2010QoL and SF\u201012 are useful to determine QoL in patients with IF. AGR was associated with improved QoL by changing SBS\u2010related anatomy and function. Thus, AGR surgery should be included in the treatment plan whenever possible. Comorbidities should be addressed interdisciplinarily to improve QoL.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ncp.11253","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T21:58:29Z","timestamp":1734040709000},"page":"147-155","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A cross\u2010sectional observational study of quality of life in adult short bowel syndrome patients: What role does autologous gut reconstruction play?"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1313-6963","authenticated-orcid":false,"given":"Julia","family":"Braun","sequence":"first","affiliation":[{"name":"Department of Surgery University Hospital of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Christian","family":"Arensmeyer","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annekristin","family":"Hausen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I University Hospital of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verena","family":"Stolz","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter Sebastian","family":"Keller","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Amarell","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I University Hospital of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Lurje","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Heidelberg Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nico","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg C.","family":"Kalff","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin W.","family":"von Websky","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital of Bonn Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Orpha. 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