{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:59:04Z","timestamp":1772999944567,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:00:00Z","timestamp":1741132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:00:00Z","timestamp":1741132800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K21639 to Maeda"],"award-info":[{"award-number":["23K21639 to Maeda"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sarcopenia is a progressive loss of skeletal muscle mass and strength that can also occur in younger adults. The validity of the SARC\u2010F questionnaire in younger populations has not been extensively investigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study was conducted using medical records of patients aged &lt;65 years who were admitted to and discharged from a 900\u2010bed university hospital between April 2019 and March 2021. The SARC\u2010F score was documented upon admission. Associations between SARC\u2010F scores and mortality were evaluated through receiver operating characteristic (ROC) curve analysis and Cox proportional hazards models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      \u2009A total of 12,743 patients were included (mean age, 47 [IQR 35\u201356] years; 56.3% women). During the observation period, mortality rates were 0.3%, 1.0%, 2.0%, and 3.3% for those aged 18\u201334, 34\u201346, 47\u201355, and 56\u201364 years, respectively. The ROC analysis showed that SARC\u2010F scores at admission had a significant area under the ROC curve (0.721, IQR 0.678\u20130.764;\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001) for predicting mortality. Using mortality during the observation period and in\u2010hospital death as external criteria, the optimal SARC\u2010F cutoff score was 1. Cox proportional hazards analysis revealed that a SARC\u2010F score \u22651 was associated with significantly higher hazard ratios across all age groups (ranging from 3.77 to 9.47; all\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Higher SARC\u2010F scores among younger adults were significantly associated with mortality. Early identification and intervention for individuals with SARC\u2010F scores \u22651 may help mitigate risks related to sarcopenia in younger populations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ncp.11284","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T17:13:09Z","timestamp":1741713189000},"page":"1203-1211","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["SARC\u2010F questionnaire and its predictive value for mortality risk in hospitalized younger adults: A retrospective study"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3684-3240","authenticated-orcid":false,"given":"Yuria","family":"Ishida","sequence":"first","affiliation":[{"name":"Department of Nutrition Aichi Medical University Hospital Nagakute Japan"},{"name":"Department of Palliative and Supportive Medicine, Graduate School of Medicine Aichi Medical University Nagakute Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7132-7818","authenticated-orcid":false,"given":"Keisuke","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Palliative and Supportive Medicine, Graduate School of Medicine Aichi Medical University Nagakute Japan"},{"name":"Nutrition Therapy Support Center Aichi Medical University Hospital Nagakute Japan"},{"name":"Department of Geriatric Medicine Hospital, National Center for Geriatrics and Gerontology Obu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akio","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Palliative and Supportive Medicine, Graduate School of Medicine Aichi Medical University Nagakute Japan"},{"name":"Department of Rehabilitation Medicine Mie University Graduate School of Medicine Tsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5709-4541","authenticated-orcid":false,"given":"Junko","family":"Ueshima","sequence":"additional","affiliation":[{"name":"Department of Palliative and Supportive Medicine, Graduate School of Medicine Aichi Medical University Nagakute Japan"},{"name":"Department of Geriatric Medicine Hospital, National Center for Geriatrics and Gerontology Obu Japan"},{"name":"Department of Nutritional Service NTT Medical Center Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayano","family":"Nagano","sequence":"additional","affiliation":[{"name":"Department of Palliative and Supportive Medicine, Graduate School of Medicine Aichi Medical University Nagakute Japan"},{"name":"Department of Nursing Nishinomiya Kyoritsu Neurosurgical Hospital Nishinomiya 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