{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T07:54:26Z","timestamp":1782978866001,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study aimed to evaluate the effects of different doses of vitamin D supplementation (400 and 800\u2009IU) on the development of necrotizing enterocolitis (NEC) and potential differences in the clinical course of the disease in preterm infants. In addition, the potential correlation between D levels and NEC stage severity was assessed. Medical records of 363 preterm infants (gestational age &lt;32 weeks) were retrospectively reviewed. Infants who developed NEC were divided into two groups based on the dose of vitamin D supplementation (400 and 800\u2009IU\/day). A comparison was made between the two groups with respect to demographic data, the severity of NEC, maternal and infant vitamin D levels, length of hospital stay, incidence of sepsis, and mortality rates. The incidence of NEC was significantly lower during the period when 800\u2009IU of vitamin D was administered (7.7%) compared with the period when 400\u2009IU was administered (12.6%). No significant differences were observed between the two groups in terms of NEC stage, mortality rates, or length of hospital stay. An inverse correlation was found between maternal and infant vitamin D levels and NEC stage severity, suggesting that the role of vitamin D metabolism in NEC pathogenesis may be more complex.<\/jats:p>","DOI":"10.1002\/ncp.11303","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T03:35:01Z","timestamp":1745292901000},"page":"1219-1224","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of the effects of different doses of vitamin D supplementation on the development of necrotizing enterocolitis: A retrospective study"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1010-3324","authenticated-orcid":false,"given":"T\u00fclin","family":"\u00d6zta\u015f","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery University of Health Sciences Diyarbak\u0131r Gazi Ya\u015fargil Training and Research Hospital Diyarbak\u0131r Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nil\u00fcfer Matur","family":"Okur","sequence":"additional","affiliation":[{"name":"Department of Neonatology University of Health Sciences Diyarbak\u0131r Gazi Ya\u015fargil Training and Research Hospital Diyarbak\u0131r Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zlem Leyla","family":"\u015eero","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Health Sciences Diyarbak\u0131r Gazi Ya\u015fargil Training and Research Hospital Diyarbak\u0131r Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S446378"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.1048322"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2023.105917"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2017.18"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.744504"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0973217920987662"},{"issue":"1","key":"e_1_2_9_8_1","first-page":"6","article-title":"The correlation between levels of vitamin D (25(HD)D) and the occurrence of necrotizing enterocolitis (NEC) in preterm infants","volume":"4","author":"Sulistijono E","year":"2023","journal-title":"Pediatr Sci J"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060520952275"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.604899"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.15761\/PD.1000208"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2017.1361925"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.1107404"},{"issue":"3","key":"e_1_2_9_14_1","first-page":"178","article-title":"Relationship between vitamin D deficiency and necrotizing enterocolitis in preterm infants. 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