{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T05:46:57Z","timestamp":1782107217137,"version":"3.54.5"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T00:00:00Z","timestamp":1782000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T00:00:00Z","timestamp":1782000000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Gastrostomy tube placement is a common intervention for long\u2010term nutrition in people with dysphagia. Minimising complications such as tube dislodgement is integral in gastrostomy management, as unplanned replacements may require urgent care to prevent stoma closure. Anecdotally, people living with motor neurone disease (plwMND) have frequent complications, although the frequency compared to other conditions remains unknown. This single\u2010centre retrospective audit aimed to quantify and compare gastrostomy\u2010related complications between MND and other conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All adults managed with a gastrostomy from 2016 to 2021 attending a single centre, dietitian\u2010led gastrostomy service were included. The service database and medical records were screened for complications including unplanned tube replacements, infection, hypergranulation tissue, compromised tube integrity or dislodgement and their frequency was compared in those with MND and in those with other conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009193 replacement gastrostomy tubes were required in\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200951 individuals. People living with MND had a statistically nonsignificantly lower rate and likelihood of first unplanned replacement compared to other conditions after adjustment for age (HR 0.42). Modelling demonstrated a reduced risk of unplanned replacement with a history of previous infection and hypergranulation tissue, and an increased risk with a history of compromised tube integrity and previous displacement in plwMND. Of unplanned replacements, 48% occurred between 90 to 180 days, with tube integrity the most frequently associated complication.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>People living with MND were more likely to experience hypergranulation tissue but did not have a higher rate of unplanned tube replacements compared to those with other conditions. People experiencing higher rates of unplanned gastrostomy replacements may benefit from strategies to reduce complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ncp.70140","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T04:47:42Z","timestamp":1782103662000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Incidence of unplanned gastrostomy tube replacements and associated complications in people with motor neurone disease and other conditions: A retrospective audit of an Australian dietitian\u2010led clinic"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2153-1200","authenticated-orcid":false,"given":"Emily","family":"Farrugia","sequence":"first","affiliation":[{"name":"Allied Health, Northern Health Melbourne Victoria Australia"},{"name":"School of Allied Health, Human Services and Sport La Trobe University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanelle","family":"Bailey","sequence":"additional","affiliation":[{"name":"Allied Health, Northern Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam I.","family":"Semciw","sequence":"additional","affiliation":[{"name":"Allied Health, Northern Health Melbourne Victoria Australia"},{"name":"School of Allied Health, Human Services and Sport La Trobe University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mani","family":"Suleiman","sequence":"additional","affiliation":[{"name":"Northern Centre for Health Education and Research, Northern Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Tacey","sequence":"additional","affiliation":[{"name":"Austin Health Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline J.","family":"Tuck","sequence":"additional","affiliation":[{"name":"Department of Allied Health, School of Health Sciences Swinburne University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6517-6507","authenticated-orcid":false,"given":"Liam M.","family":"Hannan","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Medicine Northern Health Melbourne Victoria Australia"},{"name":"Institute for Breathing and Sleep, Austin Health Heidelberg Victoria Australia"},{"name":"Faculty of Medicine, Dentistry and Health Sciences University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,21]]},"reference":[{"issue":"1","key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.clnu.2017.09.003","article-title":"ESPEN guideline: Clinical nutrition in neurology","volume":"37","author":"Burgos R","year":"2018","journal-title":"Clin Nutr"},{"issue":"15","key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1212\/WNL.0b013e3181bc01a4","article-title":"Practice parameter update: The care of the patient with amyotrophic lateral sclerosis: Drug, nutritional, and respiratory therapies (an evidence\u2010based review). 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