{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T05:47:17Z","timestamp":1782107237618,"version":"3.54.5"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T00:00:00Z","timestamp":1782000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T00:00:00Z","timestamp":1782000000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dementia with Lewy bodies (DLB)\u00a0is a multisystem neurodegenerative disorder often accompanied by autonomic and neuropsychiatric symptoms. Nutritional impairment is increasingly recognized yet under\u2010characterized in DLB. DLB was chosen due to its early multisystem involvement, including brainstem\u2010mediated autonomic and sleep disturbances, which may uniquely affect nutrition. This study evaluated nutritional status and its associations with cognitive, mood, autonomic, and sleep\u2010related features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Seventy patients with probable DLB (2017 McKeith criteria) were retrospectively included. Cases of Parkinson's disease dementia or other Lewy body\u2010related conditions were excluded. Nutritional status was assessed with the Mini Nutritional Assessment\u2010Short Form (MNA\u2010SF). Cognitive function (Addenbrooke's Cognitive Examination, ACE\u2010III), depressive symptoms (Geriatric Depression Scale, GDS), motor severity (Hoehn and Yahr staging), sleep disturbances (Rapid Eye Movement Sleep Behavior Disorder, RBD, insomnia), and autonomic symptoms (urinary incontinence, constipation, orthostatic hypotension) were extracted from clinical records. Multivariable logistic, ordinal regression, and hierarchical cluster analyses were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Normal nutrition was observed in 14.3% of patients, 60.0% were at risk, and 25.7% were malnourished. Malnutrition was significantly associated with lower ACE\u2010III and higher GDS scores (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). RBD and urinary incontinence differed across nutritional groups. Ordinal regression showed age and female sex independently associated with worse nutritional status. Cluster analysis identified a high\u2010risk phenotype with greater cognitive, depressive, autonomic, and sleep\u2010related burden linked to malnutrition.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Malnutrition is highly prevalent in DLB and correlates with cognitive, psychiatric, autonomic, and sleep\u2010related features. These associations support that nutritional impairment reflects the multisystem disease burden. Early identification of patients with combined deficits may help target those at risk and guide comprehensive management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ncp.70143","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T04:57:37Z","timestamp":1782104257000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Malnutrition and clinical correlates in dementia with Lewy bodies: A retrospective cross\u2010sectional study"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7274-025X","authenticated-orcid":false,"given":"Ozlem","family":"Totuk","sequence":"first","affiliation":[{"name":"Department of Neurology Hamidiye Faculty of Medicine, Sancaktepe Prof. Dr. Ilhan Varank Training and Research Hospital, University of Health Sciences Istanbul T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4199-442X","authenticated-orcid":false,"given":"Ozge","family":"Gonul Oner","sequence":"additional","affiliation":[{"name":"Department of Neurology Istanbul Provincial Health Directorate, Goztepe Prof. Dr. Suleyman Yalcin City Hospital Istanbul T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,21]]},"reference":[{"issue":"6","key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1016\/j.clnu.2024.04.039","article-title":"ESPEN guideline on nutrition and hydration in dementia: Update 2024","volume":"43","author":"Volkert D","year":"2024","journal-title":"Clin Nutr"},{"issue":"4","key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.3233\/JAD-200961","article-title":"Association of malnutrition with functional and cognitive trajectories in people living with dementia: a five\u2010year follow\u2010up study","volume":"79","author":"Borda MG","year":"2021","journal-title":"J Alzheimer's Dis"},{"issue":"10004","key":"e_1_2_10_4_1","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1016\/S0140-6736(15)00462-6","article-title":"Lewy body dementias","volume":"386","author":"Walker Z","year":"2015","journal-title":"The Lancet"},{"issue":"1","key":"e_1_2_10_5_1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1212\/WNL.0000000000004058","article-title":"Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortiu","volume":"89","author":"McKeith IG","year":"2017","journal-title":"Neurology"},{"issue":"4","key":"e_1_2_10_6_1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/alzrt274","article-title":"The clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosis","volume":"6","author":"Donaghy PC","year":"2014","journal-title":"Alzheimers Res Ther"},{"issue":"5","key":"e_1_2_10_7_1","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S1474-4422(13)70054-1","article-title":"Idiopathic REM sleep behaviour disorder in the development of Parkinson's disease","volume":"12","author":"Boeve BF","year":"2013","journal-title":"Lancet Neurol"},{"issue":"2","key":"e_1_2_10_8_1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S1474-4422(19)30153-X","article-title":"New evidence on the management of Lewy body dementia","volume":"19","author":"Taylor JP","year":"2020","journal-title":"Lancet Neurol"},{"issue":"1","key":"e_1_2_10_9_1","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2377-13-140","article-title":"Dysphagia in Lewy body dementia: a clinical observational study of swallowing function by videofluoroscopic examination","volume":"13","author":"Londos E","year":"2013","journal-title":"BMC Neurol"},{"issue":"12","key":"e_1_2_10_10_1","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1017\/S1041610224000346","article-title":"Eating problems in people with dementia with Lewy bodies: associations with various symptoms and the physician's understanding","volume":"36","author":"Shinagawa S","year":"2024","journal-title":"Int Psychogeriatr"},{"issue":"6","key":"e_1_2_10_11_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0157053","article-title":"Malnutrition in Alzheimer's disease, dementia with Lewy bodies, and frontotemporal lobar degeneration: comparison using serum albumin, total protein, and hemoglobin level","volume":"11","author":"Koyama A","year":"2016","journal-title":"PLoS One"},{"issue":"10","key":"e_1_2_10_12_1","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1016\/j.jamda.2020.06.051","article-title":"The relationship between dementia subtypes and nutritional parameters in older adults","volume":"21","author":"Soysal 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elderly","volume":"12","author":"Ertan T","year":"2000","journal-title":"Int Psychogeriatr"},{"key":"e_1_2_10_19_1","doi-asserted-by":"crossref","first-page":"441","DOI":"10.2147\/NDT.S151253","article-title":"Addenbrooke's Cognitive Examination III in the diagnosis of dementia: a critical review","volume":"15","author":"Bruno D","year":"2019","journal-title":"Neuropsychiatr Dis Treat"},{"issue":"1","key":"e_1_2_10_20_1","doi-asserted-by":"crossref","DOI":"10.1111\/1460-6984.13147","article-title":"The Turkish validity and reliability of Addenbrooke's Cognitive Examination III","volume":"60","author":"Parlak MM","year":"2025","journal-title":"Int J Lang Commun Disord"},{"issue":"2","key":"e_1_2_10_21_1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1212\/CON.0000000000000309","article-title":"Lewy body dementias: dementia with Lewy bodies and Parkinson disease dementia","volume":"22","author":"Gomperts 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