{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T09:52:56Z","timestamp":1791021176177,"version":"4.1.0"},"reference-count":54,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:00:00Z","timestamp":1790985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:00:00Z","timestamp":1790985600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nut in Clin Prac"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This pilot study aimed to evaluate the effect of nutritional counseling\/education interventions focusing on levodopa food\u2013drug interactions on the physical and mental quality of life of patients with Parkinson's disease (PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A quasi\u2010experimental pre\u2013post design was used. Thirty participants with PD for at least 1 year were selected from pharmacies in Konya, T\u00fcrkiye. Participants completed an ad hoc, unvalidated questionnaire that included the Short Form\u201012 (SF\u201012) quality\u2010of\u2010life evaluation as well as other questions regarding socio\u2010demographic data, general eating habits, and 3\u2010day food consumption records prior to nutritional counseling\/education intervention. After baseline data collection, each participant received one\u2010on\u2010one nutritional counseling\/education. Four weeks post\u2010intervention, participants were surveyed for 3\u2010day dietary records and repeated the SF\u201012 evaluation. The dietary data were processed using the Nutrition Information System Software (BEBiS 8.1). A registered dietitian performed all nutritional analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean age of participants was 66.8\u2009\u00b1\u20097.2 years, and the mean body mass index was 27.5\u2009\u00b1\u20093.3\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      . The intervention resulted in statistically significant enhancements in physical and mental SF\u201012 scores (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05). Participants showed decreased protein intake (from 0.87\u2009\u00b1\u20090.4 to 0.78\u2009\u00b1\u20090.3\u2009g\/kg), lower consumption of large neutral amino acids (phenylalanine, tryptophan, and tyrosine), and decreased total daily energy intake.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Short\u2010term nutritional counseling\/education targeting food\u2013drug interactions can improve quality of life and dietary habits in people with PD. To further validate and expand upon these promising findings, the long\u2010term efficacy of such targeted nutritional interventions should be demonstrated in future large\u2010scale, randomized controlled trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ncp.70184","type":"journal-article","created":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:56:12Z","timestamp":1791017772000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of food\u2013drug interaction\u2010oriented nutritional education on quality of life in Parkinson's disease: A pilot quasi\u2010experimental study"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7801-7932","authenticated-orcid":false,"given":"Mustafa","family":"\u00d6zg\u00fcr","sequence":"first","affiliation":[{"name":"Department of Nutrition and Dietetics Faculty of Health Sciences, Burdur Mehmet Akif Ersoy University Burdur T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0992-3450","authenticated-orcid":false,"given":"Zehra","family":"Balo\u011flu","sequence":"additional","affiliation":[{"name":"Freelance Clinic Dietitian  T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0555-4304","authenticated-orcid":false,"given":"Merve","family":"Horan","sequence":"additional","affiliation":[{"name":"Freelance Clinic Dietitian  T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nur","family":"Ta\u015f\u00e7i","sequence":"additional","affiliation":[{"name":"Freelance Clinic Dietitian  T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,3]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Summary Report on Proceedings Minutes and Final Acts of the International Health Conference","author":"World Health Organization","year":"1948"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.03.017"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.3c00254"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30029-8"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.14.2.223"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-1146-3_17"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.48095\/cccsnn2020633"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30295-3"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-7568(24)00094-1"},{"issue":"2","key":"e_1_2_11_11_1","first-page":"98","article-title":"Prevalence and clinical features of idiopathic Parkinson's disease in Western Turkey","volume":"59","author":"G\u00fcler S","year":"2022","journal-title":"Noro Psikiyatr Ars"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.979826"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.13549"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.976316"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/advances\/nmab060"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-89835-5.00029-6"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14153240"},{"key":"e_1_2_11_18_1","unstructured":"American Parkinson Disease Association.Good Nutrition and Parkinson's Disease.American Parkinson Disease Association. 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