{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T11:11:48Z","timestamp":1788606708356,"version":"build-2803163510"},"reference-count":150,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T00:00:00Z","timestamp":1703894400000},"content-version":"vor","delay-in-days":29,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NIH R21NS133531"],"award-info":[{"award-number":["NIH R21NS133531"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuroprotection"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Exosome\u2010based treatments are gaining traction as a viable approach to addressing the various issues faced by an ischemic stroke. These extracellular vesicles, mainly produced by mesenchymal stem cells, exhibit many properties with substantial therapeutic potential. Exosomes are particularly appealing for stroke therapy because of their low immunogenicity, effective cargo transport, and ability to cross the blood\u2013brain barrier. Their diverse effects include neuroprotection, angiogenesis stimulation, inflammatory response modulation, and cell death pathway attenuation, synergistically promoting neuronal survival, tissue regeneration, and functional recovery. Exosomes also show potential as diagnostic indicators for early stroke identification and customized treatment options. Despite these promising qualities, current exosome\u2010based therapeutics have some limitations. The heterogeneity of exosome release among cell types, difficulty in standardization and isolation techniques, and complications linked to dosage and targeted administration necessitates extensive investigation. It is critical to thoroughly understand exosomal processes and their complicated interactions within the cellular milieu. To improve the practicality and efficacy of exosome\u2010based medicines, research efforts must focus on improving production processes, developing robust evaluation criteria, and developing large\u2010scale isolation techniques. Altogether, exosomes\u2019 multifunctional properties offer a new route for transforming stroke treatment and significantly improving patient outcomes.<\/jats:p>","DOI":"10.1002\/nep3.30","type":"journal-article","created":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T15:20:23Z","timestamp":1703949623000},"page":"99-116","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Mesenchymal stem cell\u2010derived exosomes: Shaping the next era of stroke treatment"],"prefix":"10.1002","volume":"1","author":[{"given":"Arshi","family":"Waseem","sequence":"first","affiliation":[{"name":"Laboratory for Stem Cell &amp; Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College Hospital Era University, Sarfarazganj Lucknow India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Saudamini","sequence":"additional","affiliation":[{"name":"Laboratory for Stem Cell &amp; Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College Hospital Era University, Sarfarazganj Lucknow India"},{"name":"Department of Biotechnology Central University of South Bihar Gaya India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rizwanul","family":"Haque","sequence":"additional","affiliation":[{"name":"Department of Biotechnology Central University of South Bihar Gaya India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslaw","family":"Janowski","sequence":"additional","affiliation":[{"name":"Center for Advanced Imaging Research, Department of Diagnostic Radiology and Nuclear Medicine University of Maryland Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6147-9399","authenticated-orcid":false,"given":"Syed S.","family":"Raza","sequence":"additional","affiliation":[{"name":"Laboratory for Stem Cell &amp; Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College Hospital Era University, Sarfarazganj Lucknow India"},{"name":"Department of Stem Cell Biology and Regenerative Medicine, Era's Lucknow Medical College Hospital Era University, Sarfarazganj Lucknow India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,30]]},"reference":[{"key":"e_1_2_22_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21197380"},{"key":"e_1_2_22_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8827874"},{"key":"e_1_2_22_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2019.146362"},{"key":"e_1_2_22_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-018-1005-z"},{"key":"e_1_2_22_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.020465"},{"key":"e_1_2_22_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-33030-9"},{"key":"e_1_2_22_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2017.07.004"},{"key":"e_1_2_22_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.12386"},{"key":"e_1_2_22_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-020-02622-3"},{"key":"e_1_2_22_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkr828"},{"key":"e_1_2_22_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnanoscienceau.1c00062"},{"key":"e_1_2_22_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2020.113518"},{"key":"e_1_2_22_14_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X19666210203161559"},{"key":"e_1_2_22_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2023.100608"},{"key":"e_1_2_22_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2567"},{"key":"e_1_2_22_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-017-3816-z"},{"key":"e_1_2_22_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2009.08.016"},{"key":"e_1_2_22_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2018.01.059"},{"key":"e_1_2_22_20_1","doi-asserted-by":"publisher","DOI":"10.3402\/jev.v4.27066"},{"key":"e_1_2_22_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/0963689718816990"},{"key":"e_1_2_22_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2015.02.010"},{"key":"e_1_2_22_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-017-2595-9"},{"key":"e_1_2_22_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2017.125"},{"key":"e_1_2_22_25_1","doi-asserted-by":"publisher","DOI":"10.1134\/S0006297920020054"},{"key":"e_1_2_22_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21207568"},{"key":"e_1_2_22_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/ncrna7010004"},{"key":"e_1_2_22_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.115087"},{"key":"e_1_2_22_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2019.11.006"},{"key":"e_1_2_22_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells8080886"},{"key":"e_1_2_22_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms221810045"},{"key":"e_1_2_22_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.646927"},{"key":"e_1_2_22_33_1","doi-asserted-by":"publisher","DOI":"10.25259\/SNI_1174_2021"},{"key":"e_1_2_22_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms15034142"},{"key":"e_1_2_22_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awr063"},{"key":"e_1_2_22_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2004.09.020"},{"key":"e_1_2_22_37_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-22-5921"},{"key":"e_1_2_22_38_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-023-02738-5"},{"key":"e_1_2_22_39_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00133"},{"key":"e_1_2_22_40_1","doi-asserted-by":"publisher","DOI":"10.3325\/cmj.2019.60.439"},{"key":"e_1_2_22_41_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.357900"},{"key":"e_1_2_22_42_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.11.JNS14770"},{"key":"e_1_2_22_43_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2018.5711"},{"key":"e_1_2_22_44_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S209636"},{"key":"e_1_2_22_45_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2019.00209"},{"key":"e_1_2_22_46_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1522297113"},{"key":"e_1_2_22_47_1","doi-asserted-by":"publisher","DOI":"10.4252\/wjsc.v12.i8.814"},{"key":"e_1_2_22_48_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-101512-122326"},{"key":"e_1_2_22_49_1","doi-asserted-by":"publisher","DOI":"10.5966\/sctm.2015-0078"},{"key":"e_1_2_22_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-019-1602-5"},{"key":"e_1_2_22_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2010.105"},{"key":"e_1_2_22_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-018-0668-1"},{"key":"e_1_2_22_53_1","doi-asserted-by":"publisher","DOI":"10.5966\/sctm.2015-0197"},{"key":"e_1_2_22_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10081959"},{"key":"e_1_2_22_55_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S271519"},{"key":"e_1_2_22_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.1409"},{"key":"e_1_2_22_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.1129"},{"key":"e_1_2_22_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2017.04.010"},{"key":"e_1_2_22_59_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.12902"},{"key":"e_1_2_22_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2020.118403"},{"key":"e_1_2_22_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2013.152"},{"key":"e_1_2_22_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-021-00483-2"},{"key":"e_1_2_22_63_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.121.035821"},{"key":"e_1_2_22_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-018-1071-9"},{"key":"e_1_2_22_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2018.08.021"},{"key":"e_1_2_22_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-020-02998-0"},{"key":"e_1_2_22_67_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.202466"},{"key":"e_1_2_22_68_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13036-019-0193-0"},{"key":"e_1_2_22_69_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-019-0461-7"},{"key":"e_1_2_22_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep44433"},{"key":"e_1_2_22_71_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2017.00205"},{"key":"e_1_2_22_72_1","doi-asserted-by":"publisher","DOI":"10.1177\/0963689717738256"},{"key":"e_1_2_22_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2020.06.037"},{"key":"e_1_2_22_74_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.780897"},{"key":"e_1_2_22_75_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.27519"},{"key":"e_1_2_22_76_1","doi-asserted-by":"publisher","DOI":"10.1159\/000490078"},{"key":"e_1_2_22_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1596"},{"key":"e_1_2_22_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep33038"},{"key":"e_1_2_22_79_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2019.00240"},{"key":"e_1_2_22_80_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2226-19.2020"},{"key":"e_1_2_22_81_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-016-9851-0"},{"key":"e_1_2_22_82_1","doi-asserted-by":"publisher","DOI":"10.3727\/096368916X693031"},{"key":"e_1_2_22_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2019.06.019"},{"key":"e_1_2_22_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.1409"},{"key":"e_1_2_22_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-019-00115-w"},{"key":"e_1_2_22_86_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-019-1207-z"},{"key":"e_1_2_22_87_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.30879"},{"key":"e_1_2_22_88_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10121886"},{"key":"e_1_2_22_89_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2022.899887"},{"key":"e_1_2_22_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2017.62"},{"key":"e_1_2_22_91_1","doi-asserted-by":"publisher","DOI":"10.1080\/21655979.2021.2016094"},{"key":"e_1_2_22_92_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.84493"},{"key":"e_1_2_22_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2016.11.011"},{"key":"e_1_2_22_94_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S289914"},{"key":"e_1_2_22_95_1","doi-asserted-by":"publisher","DOI":"10.1080\/21655979.2021.2012402"},{"key":"e_1_2_22_96_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom10050707"},{"key":"e_1_2_22_97_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.29601"},{"key":"e_1_2_22_98_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S248892"},{"key":"e_1_2_22_99_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000130526.20854.fa"},{"key":"e_1_2_22_100_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11011-022-00997-4"},{"issue":"3","key":"e_1_2_22_101_1","first-page":"935","article-title":"Bone marrow mesenchymal stem cells\u2010secreted exosomal H19 modulates lipopolysaccharides\u2010stimulated microglial M1\/M2 polarization and alleviates inflammation\u2010mediated neurotoxicity","volume":"13","author":"Zong L","year":"2021","journal-title":"Am J Transl Res"},{"key":"e_1_2_22_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2022.106748"},{"key":"e_1_2_22_103_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00556"},{"key":"e_1_2_22_104_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-017-1017-0"},{"key":"e_1_2_22_105_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e328352ede6"},{"key":"e_1_2_22_106_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-019-1516-2"},{"key":"e_1_2_22_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11481-015-9613-1"},{"key":"e_1_2_22_108_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.336871"},{"key":"e_1_2_22_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2018.02.015"},{"key":"e_1_2_22_110_1","first-page":"1","article-title":"Adipose\u2010derived mesenchymal stem cells promote M2 macrophage phenotype through exosomes","volume":"2019","author":"Heo JS","year":"2019","journal-title":"Stem Cells Int"},{"key":"e_1_2_22_111_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-31707-9"},{"key":"e_1_2_22_112_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.33872"},{"key":"e_1_2_22_113_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10020-021-00324-0"},{"key":"e_1_2_22_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2019.105689"},{"key":"e_1_2_22_115_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2019.1630223"},{"key":"e_1_2_22_116_1","doi-asserted-by":"publisher","DOI":"10.1002\/jev2.12024"},{"key":"e_1_2_22_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2021.113700"},{"key":"e_1_2_22_118_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12015-021-10315-7"},{"key":"e_1_2_22_119_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-019-1522-4"},{"key":"e_1_2_22_120_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202300317RRR"},{"key":"e_1_2_22_121_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-023-01862-x"},{"key":"e_1_2_22_122_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.881809"},{"key":"e_1_2_22_123_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abf0529"},{"key":"e_1_2_22_124_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics9010004"},{"key":"e_1_2_22_125_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43188-020-00043-4"},{"key":"e_1_2_22_126_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15040972"},{"key":"e_1_2_22_127_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-023-05639-w"},{"key":"e_1_2_22_128_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-022-01509-9"},{"key":"e_1_2_22_129_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0163645"},{"key":"e_1_2_22_130_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2017.00057"},{"key":"e_1_2_22_131_1","doi-asserted-by":"publisher","DOI":"10.2174\/1567202614666171005153434"},{"key":"e_1_2_22_132_1","doi-asserted-by":"publisher","DOI":"10.1159\/000488365"},{"key":"e_1_2_22_133_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-018-1196-z"},{"key":"e_1_2_22_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2021.136004"},{"key":"e_1_2_22_135_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000086466.32421.F4"},{"key":"e_1_2_22_136_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2018.00309"},{"key":"e_1_2_22_137_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.01911.x"},{"key":"e_1_2_22_138_1","doi-asserted-by":"publisher","DOI":"10.1080\/20013078.2020.1809065"},{"key":"e_1_2_22_139_1","doi-asserted-by":"publisher","DOI":"10.3390\/v7072810"},{"key":"e_1_2_22_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature23282"},{"issue":"5","key":"e_1_2_22_141_1","first-page":"379","article-title":"Dosage and passage dependent neuroprotective effects of exosomes derived from rat bone marrow mesenchymal stem cells: an in vitro analysis","volume":"18","author":"Venugopal C","year":"2018","journal-title":"Curr Gene Ther"},{"key":"e_1_2_22_142_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-020-01601-1"},{"key":"e_1_2_22_143_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05901"},{"key":"e_1_2_22_144_1","doi-asserted-by":"publisher","DOI":"10.3402\/jev.v4.26316"},{"key":"e_1_2_22_145_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S307843"},{"key":"e_1_2_22_146_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-021-00879-4"},{"key":"e_1_2_22_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2016.09.002"},{"key":"e_1_2_22_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111314"},{"key":"e_1_2_22_149_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0NR07516G"},{"key":"e_1_2_22_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.119942"},{"key":"e_1_2_22_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.10.012"}],"container-title":["Neuroprotection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nep3.30","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T05:14:30Z","timestamp":1720156470000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nep3.30"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":150,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1002\/nep3.30"],"URL":"https:\/\/doi.org\/10.1002\/nep3.30","archive":["Portico"],"relation":{},"ISSN":["2770-7296","2770-730X"],"issn-type":[{"value":"2770-7296","type":"print"},{"value":"2770-730X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"2023-08-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}