{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T01:21:14Z","timestamp":1771464074739,"version":"3.50.1"},"reference-count":63,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,10,11]],"date-time":"2004-10-11T00:00:00Z","timestamp":1097452800000},"content-version":"vor","delay-in-days":4485,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Neurobiol."],"published-print":{"date-parts":[[1992,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In contrast to the situation in mammals and birds, neurons in the central nervous system (CNS) of fish\u2014such as the retinal ganglion cells\u2014are capable of regenerating their axons and restoring vision. Special properties of the glial cells and the neurons of the fish visual pathway appear to contribute to the success of axonal regeneration. The fish oligodendrocytes lack the axon growth inhibiting molecules that interfere with axonal extension in mammals. Instead, fish optic nerve oligodendrocytes support\u2014at least <jats:italic>in vitro<\/jats:italic>\u2014axonal elongation of fish as well as that of rat retinal axons. Moreover, the fish retinal ganglion cells re\u2010express upon injury a set of growth associated cell surface molecules and equip the regenerating axons throughout their path and up into their target, the tectum opticum with these molecules. This may indicate that the injured fish ganglion cells reactivate the cellular machinery necessary for axonal regrowth and pathfinding. Furthermore, the target itself provides positional marker molecules even in adult fish. These marker molecules are required to guide the regenerating axons back to their retinotopic home territory within the tectum. \u00a9 1992 John Wiley &amp; Sons, Inc.<\/jats:p>","DOI":"10.1002\/neu.480230508","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T03:27:39Z","timestamp":1104550059000},"page":"537-550","source":"Crossref","is-referenced-by-count":119,"title":["Trying to understand axonal regeneration in the CNS of fish"],"prefix":"10.1002","volume":"23","author":[{"given":"Claudia A. 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