{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T23:51:49Z","timestamp":1770421909025,"version":"3.49.0"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T00:00:00Z","timestamp":1739059200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing Open"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aims to evaluate the effectiveness of supportive nursing care interventions in reducing depression and anxiety among mothers with infants in the neonatal intensive care unit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Systematic review and meta\u2010analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Randomised controlled trials conducted in mothers with infants admitted to the neonatal intensive care unit with any form of supportive nursing interventions compared to no intervention or usual care in terms of either reduction in depression or reduction in anxiety level of the mothers reported in both groups were included. The GRADE approach assessed the quality of evidence, while the pooled standardised mean difference with 95% confidence intervals (CIs) was calculated using a random\u2010effects model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 18 studies were included. For depression, the pooled standardised mean difference was \u22120.24 (95% CI: \u22120.44 to \u22120.04), indicating a significant reduction in depression levels among mothers receiving supportive nursing care compared to standard care. In anxiety, pooled standardised mean difference was \u22120.61 (95% CI: \u22120.96 to \u22120.25), showing substantial reduction in anxiety levels. GRADE findings indicated moderate quality of evidence for depression and very low quality for anxiety, mainly due to heterogeneity and publication bias in anxiety outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patient or Public Contribution<\/jats:title><jats:p>No patient or public contribution.<\/jats:p><\/jats:sec>","DOI":"10.1002\/nop2.70120","type":"journal-article","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T23:05:28Z","timestamp":1739228728000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Supportive Nursing Care Intervention for Handling Depression and Anxiety Among Mothers of Neonates Admitted in Neonatal Intensive Care Unit (<scp>NICU<\/scp>): A Meta\u2010Analysis"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6899-7647","authenticated-orcid":false,"given":"Xiaohua","family":"Zhu","sequence":"first","affiliation":[{"name":"Clinical Medical Laboratory Center Children's Hospital of Shanxi Province (Maternal and Child Health Hospital of Shanxi Province)  Taiyuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8635-5293","authenticated-orcid":false,"given":"Lijuan","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shanxi Provincial Children's Hospital (Shanxi Maternal and Child Health Center)  Taiyuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.outlook.2021.05.012"},{"issue":"3","key":"e_1_2_11_3_1","first-page":"59","article-title":"The Effectiveness of Participatory Care Program in Neonatal Intensive Care Unit on State Anxiety of Mothers of Preterm Newborns","volume":"14","author":"Bastani F.","year":"2012","journal-title":"Journal of Babol University of Medical Sciences"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jts.20626"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1138741600001578"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S91632"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2014.0037"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2023.105717"},{"issue":"10","key":"e_1_2_11_9_1","article-title":"Updated Guidance For Trusted Systematic Reviews: A New Edition of The Cochrane Handbook For Systematic Reviews of Interventions","volume":"10","author":"Cumpston M.","year":"2019","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnn.2019.03.004"},{"issue":"4","key":"e_1_2_11_11_1","first-page":"195","article-title":"A New Improved Graphical and Quantitative Method for Detecting Bias in Meta\u2010Analysis","volume":"16","author":"Furuya\u2010Kanamori L.","year":"2018","journal-title":"JBI Evidence Implementation"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.08.015"},{"key":"e_1_2_11_13_1","volume-title":"Committee on the Science of Children Birth to Age 8: Deepening and Broadening the Foundation for Success; Board on Children, Youth, and Families","author":"Institute of Medicine and National Research Council","year":"2015"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cnc.2024.01.005"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-021-04336-w"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1099800412445612"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/17455057221104674"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/nur.1038"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2580"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-1870"},{"issue":"1","key":"e_1_2_11_21_1","first-page":"94","article-title":"The Effect of Creating Opportunities for Parent Empowerment Program on Maternal Stress, Anxiety, and Participation in NICU Wards in Iran","volume":"19","author":"Mianaei S. 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