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Data on sociodemographic characteristics, personality types, self\u2010esteem, anxiety, depression, sleepiness, resilience and occupational nursing stress were also collected. Multiple linear regression models were used to determine the associations among palliative care, occupational nursing stress, resilience, sleepiness, anxiety, depression, self\u2010esteem and personality traits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Palliative care was associated with nursing stress (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.36; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), death and dying (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.28; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), inadequate preparation (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.14; <jats:italic>p<\/jats:italic>\u2009=\u20090.022) and sleepiness (<jats:italic>\u03b2<\/jats:italic>\u2009=\u2009\u22120.19; <jats:italic>p<\/jats:italic>\u2009=\u20090.021). Nurses providing palliative care reported a lack of support (<jats:italic>\u03b2<\/jats:italic>\u2009=\u2009\u22120.14; <jats:italic>p<\/jats:italic>\u2009=\u20090.028), which was associated with workload (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.44) and uncertainty about patient care (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.41), <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 for both. Conflict between nurses and physicians increased the conflict among nurses (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.49; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and uncertainty about treatment (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.35; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Death and dying contributed to workload (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.23; <jats:italic>p<\/jats:italic>\u2009=\u20090.006) and uncertainty about treatment (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.23; <jats:italic>p<\/jats:italic>\u2009=\u20090.014). Nursing stress contributed to depression (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.16; <jats:italic>p<\/jats:italic>\u2009=\u20090.009) and anxiety (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.12; <jats:italic>p<\/jats:italic>\u2009=\u20090.043) and vice versa. These results support the hypothesis that palliative nursing care is related to occupational stress.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Providing palliative nursing care was associated with higher levels of occupational stress. Stress may trigger adverse health consequences such as the development of anxiety, depression and other chronic non\u2010communicable diseases. Support programs are indispensable for strengthening nurses' skills and reducing occupational stress to maintain their health and ensure high\u2010quality patient care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Implications for the Profession and\/or Patient Care<\/jats:title><jats:p>A non\u2010probabilistic convenience sample of nurses was the subject of a cross\u2010sectional study to assess the level of occupational stress of nurses who provide palliative nursing care and its impact on nurses' mental health. Occupational stress in palliative care can have negative health consequences for nurses, including the development of anxiety, depression and other chronic non\u2010communicable diseases. Consequently, the quality of nursing care may be adversely affected. 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