{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T11:58:59Z","timestamp":1785239939586,"version":"3.55.0"},"reference-count":42,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing Open"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate the efficacy of an individualised music playlist composed of preferred music genres sequenced using the Iso\u2010Principle (InMP) for immediate de\u2010escalation of agitation in dementia, compared with preferred music (PM) and treatment as usual (TAU).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A multi\u2010centre, three\u2010arm randomised controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Residential home residents with dementia and significant agitation would be randomly allocated to InMP, PM, or TAU groups. All participants would receive usual de\u2010escalation techniques when agitated. The InMP group would additionally listen to music sequenced by the Iso\u2010Principle for 30\u2009min when agitation begins, while the PM group would listen to randomly sequenced preferred music. The primary outcome is agitation level, assessed every 5\u2009min for an hour after each agitation onset. Scores from each 5\u2010min interval would be calculated to give an area\u2010under\u2010curve score to summarise the agitation level of that episode and compared across groups. Secondary outcomes include agitation frequency, behavioural and psychological symptoms severity and carer distress, measured at baseline and Week 6 using CMAI and NPI\u2010Q and analysed using GEE. Conventional content analysis of semi\u2010structured interviews with care staff would be used for implementation factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for the Profession and\/or Patient Care<\/jats:title>\n                    <jats:p>This study would employ a rigorous approach to evaluate the effects of the intervention. The findings would inform evidence\u2010based strategies for nursing practice to promptly de\u2010escalate agitation in dementia, potentially reducing reliance on medications and physical restraints, improving care quality, and alleviating carer burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Impact<\/jats:title>\n                    <jats:p>Agitation negatively impacts both residents and carers. While music interventions can reduce agitation frequency, their effectiveness for immediate de\u2010escalation and impact on carer distress remain unknown. This study addresses the knowledge gap and aims to provide practical solutions for a prevalent clinical problem.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient or Public Contribution<\/jats:title>\n                    <jats:p>Service providers commented on intervention design and outcome measurement approaches, ensuring the research addresses the needs of individuals with dementia and the protocol is practical for implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                      : NCT06104436\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nop2.70663","type":"journal-article","created":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T05:42:17Z","timestamp":1783143737000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Individualised Music Playlist Based on the Iso\u2010Principle for De\u2010Escalating Agitation in Older People With Dementia: Protocol for a\n                    <scp>RCT<\/scp>"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5651-9352","authenticated-orcid":false,"given":"Daphne Sze Ki","family":"Cheung","sequence":"first","affiliation":[{"name":"School of Nursing and Midwifery, Faculty of Health Deakin University  Burwood Victoria Australia"},{"name":"Deakin Centre for Quality and Patient Safety Research\u2014Bayside Health Partnership Institute for Health Transformation, Deakin University  Melbourne Australia"},{"name":"School of Nursing The Hong Kong Polytechnic 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