{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:10:01Z","timestamp":1790673001086,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing Open"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To analyse the clinical, technical, and demographic factors associated with tunnelled central venous catheter dysfunction in patients undergoing haemodialysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Multicentre, retrospective session\u2010level observational study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analysed 40,193 haemodialysis sessions from 743 patients with tunnelled central venous catheters. Descriptive and univariate analyses were performed to explore associations between catheter dysfunction and clinical, technical and treatment\u2010related variables. Dysfunction within a session was defined by a blood flow &lt;\u2009300\u2009mL\/min together with abnormal arterial (&lt;\u2009\u2212250\u2009mmHg) or venous (&gt;\u2009+250\u2009mmHg) pressures at baseline or 60\u2009min.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Source<\/jats:title>\n                    <jats:p>Nefrosoft clinical system (January\u2013December 2021).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>As expected from the operational definition, sessions classified as dysfunctional showed lower blood flow and more extreme arterial and venous pressures. Beyond the intradialytic markers included in the operational definition, dysfunctional sessions more frequently involved management\u2010related measures such as catheter line reversal and the use of 5% heparin locks, as well as catheter placement in the left internal jugular vein and comorbidities such as diabetes and cardiovascular disease. Because line reversal and 5% heparin locks may represent responses to poor catheter performance, these findings should be interpreted cautiously. Sessions with dysfunction also showed lower dialysis efficacy, particularly in male patients. Overall systemic anticoagulant therapy was more frequent in sessions with dysfunction, whereas overall systemic antiplatelet therapy, analysed as a binary variable, was not significantly associated with the event.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Catheter dysfunction is a frequent complication with multifactorial associations. Our findings highlight the importance of systematic clinical and technical monitoring during haemodialysis sessions. Associations identified here are descriptive and hypothesis\u2010generating; further studies with adjusted analyses are needed before conclusions about prediction or causality can be drawn.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nop2.70758","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T08:29:07Z","timestamp":1788942547000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical and Technical Factors Associated With Tunnelled Central Venous Catheter Dysfunction in Haemodialysis: A Multicentre Session\u2010Level Retrospective Study"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7427-7833","authenticated-orcid":false,"given":"Ver\u00f3nica","family":"Gimeno Hern\u00e1n","sequence":"first","affiliation":[{"name":"Departamento de Enfermer\u00eda Facultad de Enfermer\u00eda, Fisioterapia y Podolog\u00eda, Universidad 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Biom\u00e9dica, Hospital Cl\u00ednico San Carlos (IdISSC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5357-4583","authenticated-orcid":false,"given":"Ana Bel\u00e9n","family":"Rivas Paterna","sequence":"additional","affiliation":[{"name":"Departamento de Enfermer\u00eda Facultad de Enfermer\u00eda, Fisioterapia y Podolog\u00eda, Universidad Complutense de Madrid (UCM)  Madrid Spain"},{"name":"Servicio de Farmacolog\u00eda Hospital Universitario Cl\u00ednico San Carlos  Madrid Spain"},{"name":"Grupo de Investigaci\u00f3n Farmacolog\u00eda Cl\u00ednica Instituto de Investigaci\u00f3n Biom\u00e9dica, Hospital Cl\u00ednico San Carlos (IdISSC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2873-3874","authenticated-orcid":false,"given":"Guillermo","family":"Moreno","sequence":"additional","affiliation":[{"name":"Departamento de Enfermer\u00eda Facultad de Enfermer\u00eda, Fisioterapia y Podolog\u00eda, Universidad Complutense de Madrid (UCM)  Madrid Spain"},{"name":"Grupo de Investigaci\u00f3n Cardiovascular Multidisciplinar Traslacional (GICMT), \u00c1rea de Investigaci\u00f3n Cardiovascular Instituto de Investigaci\u00f3n Hospital 12 de Octubre (imas12)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5730-5217","authenticated-orcid":false,"given":"Maria Jes\u00fas","family":"Vicente\u2010Gal\u00e1n","sequence":"additional","affiliation":[{"name":"Departamento de Enfermer\u00eda Facultad de Enfermer\u00eda, Fisioterapia y Podolog\u00eda, Universidad Complutense de Madrid (UCM)  Madrid Spain"},{"name":"Consulta de Insuficiencia Cardiaca Hospital de D\u00eda\/Medicina Interna, Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n  Madrid 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