{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:59:41Z","timestamp":1790823581381,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nursing Open"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To systematically evaluate existing prediction models for medical adhesive\u2010related skin injury and assess their potential contribution to nurse\u2010led risk assessment and preventive care planning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic review and meta\u2010analysis was conducted. Seven databases were searched from inception to 25 October 2025. Studies developing prediction models for medical adhesive\u2010related skin injury in adults were assessed using the Prediction Model Risk of Bias Assessment Tool. Random\u2010effects meta\u2010analyses were used to synthesize prevalence estimates, model discrimination and common predictors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twelve studies comprising 14 prediction models were included. Reported area under the curve or C\u2010index values ranged from 0.789 to 0.960. In the nine studies included in the discrimination meta\u2010analysis, the pooled area under the curve was 0.87 (95% confidence interval: 0.84\u20130.90). All studies had a high overall risk of bias, and none performed external validation. The pooled prevalence of medical adhesive\u2010related skin injury was 22.0% (95% confidence interval: 18.5%\u201325.4%). Age over 60\u2009years, a history of medical adhesive\u2010related skin injury, allergy history, edema, study\u2010defined hypoproteinemia, and moist skin were associated with higher odds, whereas higher Braden Scale scores were associated with lower odds.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Existing models are not ready for stand\u2010alone clinical use because of their high risk of bias and lack of external validation. Further well\u2010designed studies are needed to develop and externally validate clinically useful prediction models for medical adhesive\u2010related skin injury.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for Nursing Practice<\/jats:title>\n                    <jats:p>The identified factors may help nurses prioritise closer skin assessment, surveillance, and individualised preventive care. They should be considered within a comprehensive nursing assessment rather than used as a validated risk score or intervention threshold.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>No Patient or Public Contribution<\/jats:title>\n                    <jats:p>None because this review used previously published evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p>PROSPERO registration number CRD420251179067.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/nop2.70872","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:51:23Z","timestamp":1790823083000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictive Models for Medical Adhesive\u2010Related Skin Injury: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4106-0048","authenticated-orcid":false,"given":"Yujing","family":"Gu","sequence":"first","affiliation":[{"name":"Department of Scientific Research Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital)  Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0509-7596","authenticated-orcid":false,"given":"Zhouzhou","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Scientific Research Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital)  Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Scientific Research Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital)  Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujun","family":"Fan","sequence":"additional","affiliation":[{"name":"Nursing Department Fuyang Fifth People's Hospital  Fuyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Scientific Research Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital)  Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2025.2522329"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnsa.2022.100078"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/ASW.0000000000000235"},{"issue":"19","key":"e_1_2_13_5_1","first-page":"3561","article-title":"Construction and Validation of a Risk Prediction Model for Medical Adhesive\u2010Related Skin Injury in ICU Patients","volume":"10","author":"Feng Y.","year":"2024","journal-title":"Chinese Evidence\u2010Based Nursing"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aucc.2023.02.005"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezy180"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.16823"},{"issue":"1","key":"e_1_2_13_9_1","first-page":"107","article-title":"Risk of Medical Adhesive\u2010Related Skin Injury in Patients With Colon Cancer Undergoing Chemotherapy With an Indwelling Peripherally Inserted Central Catheter","volume":"40","author":"Huang S.","year":"2020","journal-title":"Journal of Clinical and Pathological Research"},{"key":"e_1_2_13_10_1","unstructured":"Lai Y.2022.\u201cRisk Factor Analysis and Construction of a Prediction Model for Medical Adhesive\u2010Related Skin Injury at PICC Insertion Sites in Chengdu.\u201d"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0000000000000971"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/nop2.1762"},{"key":"e_1_2_13_13_1","unstructured":"Li Z.2024.\u201cConstruction and Validation of a Risk Prediction Model for Medical Adhesive\u2010Related Skin Injury in ICU Patients.\u201d"},{"issue":"23","key":"e_1_2_13_14_1","first-page":"3349","article-title":"Construction and Validation of a Risk Prediction Model for Medical Adhesive\u2010Related Skin Injury at PICC Insertion Sites","volume":"32","author":"Liu X.","year":"2023","journal-title":"Modern Journal of Integrated Traditional Chinese and Western Medicine"},{"key":"e_1_2_13_15_1","unstructured":"Long G.2022.\u201cAnalysis of Influencing Factors and Construction of a Prediction Model for Medical Adhesive\u2010Related Skin Injury in Home\u2010Based Patients With 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