{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:22:23Z","timestamp":1791084143105,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T00:00:00Z","timestamp":1655856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropsychopharm Rep"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a common side effect in patients treated with SSRIs and venlafaxine, while there is little information on SIADH in the treatment of duloxetine for pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>The patients were an 83\u2010year\u2010old Japanese male and a 71\u2010year\u2010old Japanese female. Several years earlier, they complained of pain. Accidentally, blood tests revealed hyponatremia of 110\u2009mmol\/L and 108\u2009mmol\/L 35\u2009days and 40\u2009days after initiating duloxetine 20\u2009mg\/day, respectively. The hyponatremia of both patients recovered after switching from duloxetine to mianserin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We conclude that asymptomatic SIADH was induced by use of duloxetine. Psychiatrists should be aware of this syndrome.<\/jats:p><\/jats:sec>","DOI":"10.1002\/npr2.12279","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T05:14:28Z","timestamp":1655961268000},"page":"387-390","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Asymptomatic syndrome of inappropriate secretion of antidiuretic hormone (<scp>SIADH<\/scp>) following duloxetine treatment for pain with depression: Two case reports"],"prefix":"10.1002","volume":"42","author":[{"given":"Aoi","family":"Sato","sequence":"first","affiliation":[{"name":"Department of Psychiatry Dokkyo Medical University, School of Medicine  Shimotsuga\u2010gun Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4414-3770","authenticated-orcid":false,"given":"Norio","family":"Yasui\u2010Furukori","sequence":"additional","affiliation":[{"name":"Department of Psychiatry 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