{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T10:11:44Z","timestamp":1752228704634,"version":"3.40.5"},"reference-count":7,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T00:00:00Z","timestamp":1683158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropsychopharm Rep"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Tetrahydrocannabinol acetate (THC\u2010O) is a cannabinoid\u2010based product, and few medical studies have evaluated the effects of THC\u2010O on humans. Recently, e\u2010cigarettes have become popular among teenagers and young adults worldwide. However, there have been reports of people misusing this device as a delivery system for drugs of abuse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>We herein report a case of panic attack after THC\u2010O inhalation using an e\u2010cigarette device in an 18\u2010year\u2010old male with no history of psychiatric disorders. Although he started smoking both regular cigarettes and e\u2010cigarettes in junior high school, he had never vaped delta\u20109 THC or THC\u2010O until the present episode. A total of 20\u2009min after his first inhalation of THC\u2010O, he experienced a sudden attack that lasted 2\u2009h. After this episode, he did not inhale THC\u2010O. Throughout the subsequent 6\u2009months of follow\u2010up, he maintained improvement with no panic attacks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this case, we intend to emphasize that THC\u2010O is not safe, even if the substance is regarded as loophole drug. The use of e\u2010cigarette devices might accelerate substance abuse.<\/jats:p><\/jats:sec>","DOI":"10.1002\/npr2.12345","type":"journal-article","created":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T05:24:00Z","timestamp":1683264240000},"page":"647-649","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A case of panic attack developing after <scp>THC\u2010O<\/scp> acetate inhalation using an e\u2010cigarette device"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7058-664X","authenticated-orcid":false,"given":"Norio","family":"Sugawara","sequence":"first","affiliation":[{"name":"Department of Psychiatry Dokkyo Medical University School of Medicine  Mibu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4414-3770","authenticated-orcid":false,"given":"Norio","family":"Yasui\u2010Furukori","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Dokkyo Medical University School of Medicine  Mibu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazutaka","family":"Shimoda","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Dokkyo Medical University School of Medicine  Mibu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jat\/bkac036"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2022.10.003"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2023.107620"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161212802884780"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.2019.1708999"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsr.2022.10.019"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2007.10.012"}],"container-title":["Neuropsychopharmacology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/npr2.12345","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,6]],"date-time":"2024-01-06T07:26:11Z","timestamp":1704525971000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/npr2.12345"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,4]]},"references-count":7,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1002\/npr2.12345"],"URL":"https:\/\/doi.org\/10.1002\/npr2.12345","archive":["Portico"],"relation":{},"ISSN":["2574-173X","2574-173X"],"issn-type":[{"type":"print","value":"2574-173X"},{"type":"electronic","value":"2574-173X"}],"subject":[],"published":{"date-parts":[[2023,5,4]]},"assertion":[{"value":"2023-04-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}