{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T18:59:43Z","timestamp":1781549983007,"version":"3.54.5"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T00:00:00Z","timestamp":1710115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22K15763"],"award-info":[{"award-number":["JP22K15763"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropsychopharm Rep"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study examined the association between drinking behavior patterns and depressive symptoms after alcohol abstinence in patients with alcohol use disorder (AUD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We recruited 102 AUD inpatients with baseline depressive symptoms, indicated by scores \u22656 on the Quick Inventory of Depressive Symptomatology Self\u2010Report Japanese Version (QIDS\u2010SR\u2010J) pre\u2010detoxification. Post\u20104\u2010week abstinence, remission was defined as QIDS\u2010SR\u2010J scores &lt;6. Patients were classified into remitted (<jats:italic>n<\/jats:italic>\u2009=\u200951) and persistent (<jats:italic>n<\/jats:italic>\u2009=\u200951) groups. Comparative analyses were conducted using patient profiles and the Drinking Behavior Pattern 20\u2010item Questionnaire (DBP\u201020). Logistic regression identified factors related to post\u2010abstinence persistent depression. Receiver operating characteristic curve analysis determined DBP\u201020 cutoff scores differentiating between persistent and remitted depression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The persistent group exhibited higher scores in the DBP\u201020 \u201ccoping with negative affect\u201d subscale. Logistic regression showed low education, unemployment, and using alcohol for coping as significant factors for persistent depression. Conversely, an automatic drinking pattern indicated natural remission post\u2010abstinence. A subscale score of \u22658 in alcohol use for coping, especially among unemployed patients, predicted persistent depression (sensitivity 86.8%, positive predictive value 73.3%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Unemployed patients with AUD using alcohol to cope with negative affect may experience residual depression even after detoxification. In contrast, patients with AUD with predominantly automatic drinking behavior may exhibit natural remission post\u2010abstinence.<\/jats:p><\/jats:sec>","DOI":"10.1002\/npr2.12429","type":"journal-article","created":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T08:09:35Z","timestamp":1710144575000},"page":"381-388","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Drinking behavior patterns may be associated with persistent depressive symptoms after alcohol abstinence in alcohol use disorder"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2032-3873","authenticated-orcid":false,"given":"Kazuhiro","family":"Kurihara","sequence":"first","affiliation":[{"name":"Department of Neuropsychiatry, Graduate School of Medicine University of the Ryukyus  Okinawa 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