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CGRP mAbs have been reported to be effective not only for migraine but also for other comorbidities, such as psychiatric complications in patients with migraine. However, there are no reports examining the effect of CGRP mAbs on dystonia. We treated a patient with comorbid migraine and focal task\u2010specific dystonia (writer's cramp) with a CGRP mAb (erenumab) because of an increase in monthly migraine days despite the addition of migraine prophylaxis. In this patient, erenumab treatment for 3\u2009months led to improvements in symptoms of both focal dystonia and migraine, suggesting a role for CGRP in the pathophysiology of both conditions.<\/jats:p>","DOI":"10.1002\/npr2.12444","type":"journal-article","created":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T08:55:55Z","timestamp":1712825755000},"page":"482-484","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Can calcitonin gene\u2010related peptide monoclonal antibodies ameliorate writer's cramp and migraine?"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0320-8993","authenticated-orcid":false,"given":"Keisuke","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Neurology Dokkyo Medical University  Mibu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiho","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Neurology Dokkyo Medical University  Mibu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of Neurology Dokkyo Medical University  Mibu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotaka","family":"Sakuramoto","sequence":"additional","affiliation":[{"name":"Department of Neurology Dokkyo Medical University  Mibu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mukuto","family":"Shioda","sequence":"additional","affiliation":[{"name":"Department of Neurology Dokkyo Medical University  Mibu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Hirata","sequence":"additional","affiliation":[{"name":"Department of Neurology Dokkyo Medical University  Mibu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(21)00409-9"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2022.120462"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12134526"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13456"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-018-0955-y"},{"key":"e_1_2_9_7_1","unstructured":"Japanese Headache Society.Japanese CGRP\u2010related new migraine treatment guideline.https:\/\/www.jhsnet.net\/guideline_CGRP.html"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13849"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.13529"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2887-09.2009"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102419844711"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000010740"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/03331024231212895"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-016-8373-z"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins13110751"}],"container-title":["Neuropsychopharmacology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/npr2.12444","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T05:50:34Z","timestamp":1733118634000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/npr2.12444"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,11]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/npr2.12444"],"URL":"https:\/\/doi.org\/10.1002\/npr2.12444","archive":["Portico"],"relation":{},"ISSN":["2574-173X","2574-173X"],"issn-type":[{"type":"print","value":"2574-173X"},{"type":"electronic","value":"2574-173X"}],"subject":[],"published":{"date-parts":[[2024,4,11]]},"assertion":[{"value":"2024-02-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}