{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:55:04Z","timestamp":1788778504328,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T00:00:00Z","timestamp":1729555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T00:00:00Z","timestamp":1729555200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropsychopharm Rep"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To investigate the factors associated with interoception in patients with alcohol use disorder and determine whether treatment causes changes in their interoception.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Body Perception Questionnaire\u2010Body Awareness ultra\u2010short version Japanese version (BPQ\u2010BAVSF\u2010J) was used to measure interoception in 50 alcohol\u2010dependent participants (27 in the inpatient group and 23 in the outpatient group). The BPQ\u2010BAVSF\u2010J was administered and data on aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma\u2010glutamyl transpeptidase (\u03b3\u2010GTP), mean corpuscular volume, platelet count, and Fib\u20104 index were extracted at admission and immediately before discharge for the inpatient group and at the first outpatient visit and approximately 3\u2009months after the visit for the outpatient group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean age of the 50 participants was 51.0\u2009\u00b1\u200912.3\u2009years. Significant associations were found between the BPQ\u2010BAVSF\u2010J and Fib\u20104 index and AST. The BPQ\u2010BAVSF\u2010J score significantly decreased at discharge in the inpatient group. AST, ALT, \u03b3\u2010GTP, and Fib\u20104 index of liver function were also significantly lower at discharge. In contrast, in the outpatient group, there were no significant changes in the BPQ\u2010BAVSF\u2010J score, AST level, ALT level, \u03b3\u2010GTP level, and Fib\u20104 index between at the first outpatient visit and approximately 3\u2009months after the visit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Interoception in patients with alcohol use disorder increased with worsening liver function and decreased with improvement in liver function owing to treatment. This suggests that the BPQ\u2010BAVSF\u2010J score, an easily accessible scale, may be used to detect early deterioration of liver function through regular administration.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/npr2.12491","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T02:19:46Z","timestamp":1729649986000},"page":"792-797","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Changes in interoception before and after treatment in patients with alcohol use disorder"],"prefix":"10.1002","volume":"44","author":[{"given":"Chika","family":"Shimohara","sequence":"first","affiliation":[{"name":"Department of Psychosocial Rehabilitation, Graduate School of Biomedical and Health Sciences Hiroshima University  Hiroshima Japan"},{"name":"Senogawa Hospital Senogawa Medical Corporation  Hiroshima Japan"},{"name":"Yokogawa Ekimae Clinic Senogawa Medical Corporation  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariyuki","family":"Kagaya","sequence":"additional","affiliation":[{"name":"Senogawa Hospital Senogawa Medical Corporation  Hiroshima Japan"},{"name":"Yokogawa Ekimae Clinic Senogawa Medical Corporation  Hiroshima Japan"},{"name":"KONUMA Memorial Institute of Addiction and Mental Health Senogawa Hospital  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Akita","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Infectious Disease Control and Prevention, Graduate School of Biomedical and Health Sciences Hiroshima University  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryotaro","family":"Tsukue","sequence":"additional","affiliation":[{"name":"Senogawa Hospital Senogawa Medical Corporation  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Shimohara","sequence":"additional","affiliation":[{"name":"Yokogawa Ekimae Clinic Senogawa Medical Corporation  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5727-1421","authenticated-orcid":false,"given":"Maro G.","family":"Machizawa","sequence":"additional","affiliation":[{"name":"Center for Brain, Mind &amp; KANSEI Sciences Research Hiroshima University  Hiroshima Japan"},{"name":"Xiberlinc Inc.  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