{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:03:28Z","timestamp":1753869808305,"version":"3.41.2"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004160","name":"Mazandaran University of Medical Sciences","doi-asserted-by":"publisher","award":["347"],"award-info":[{"award-number":["347"]}],"id":[{"id":"10.13039\/501100004160","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropsychopharm Rep"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The coronavirus disease 2019 (COVID\u201019) outbreak raised many concerns along with physical and mental health complications, including adjustment disorder (AD). Given the utmost importance of this issue for vulnerable groups, the present study was to investigate COVID\u201019\u2010induced AD among Iranian patients living with multiple sclerosis (MS) in 2020.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adopting a cross\u2010sectional research design, this study was performed on a statistical population of MS patients. Sampling was further done online via Porsline, as a survey tool, in Iran. In total, 247 patients were examined for the period of 2\u2009months, recruiting a sociodemographic\u2010medical information form and the Adjustment Disorder New Module (ADNM). As a final point, the data were analyzed using the SPSS Statistics software (ver. 26).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The MS patients' mean age was 36.10\u2009\u00b1\u20098.07\u2009years. 82.6% of the participants were female. The AD mean score was also 44.09\u2009\u00b1\u200913.89, at the moderate level. In this line, a significant relationship was observed between AD among patients with MS and gender (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), occupation (<jats:italic>p<\/jats:italic>\u2009=\u20090.009), a history of psychiatric disorders (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), a history of taking psychiatric medications (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), medical appointments canceled due to COVID\u201019 (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), medication shortages amid COVID\u201019 (<jats:italic>p<\/jats:italic>\u2009=\u20090.018), a history of COVID\u201019 infection (<jats:italic>p<\/jats:italic>\u2009=\u20090.018), a history of polymerase chain reaction (PCR) test for COVID\u201019 (<jats:italic>p<\/jats:italic>\u2009=\u20090.042), worry about COVID\u201019 infection (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), fear of familial COVID\u201019 infection (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), and death of friends or relatives caused by COVID\u201019 (<jats:italic>p<\/jats:italic>\u2009=\u20090.025).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present study established that AD in the MS patients was at the moderate level, and it was even associated with some distinctive variables. So, data from multicenter studies are needed to achieve better recommendations regarding screening psychiatric disorders and supportive strategies in clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.1002\/npr2.70022","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T12:02:14Z","timestamp":1746187334000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Investigating COVID\u201019\u2010Induced Adjustment Disorder Among Iranian Patients With Multiple Sclerosis in Pandemic Time"],"prefix":"10.1002","volume":"45","author":[{"given":"Elahe","family":"Samami","sequence":"first","affiliation":[{"name":"Student Research Committee Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Mohammad","family":"Baghbanian","sequence":"additional","affiliation":[{"name":"Neurology Department, School of Medicine, Booalisina Hospital Mazandaran University of Medical Sciences  Sari Iran"},{"name":"Psychosomatic Research Center, School of Medicine Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyedeh Zeynab Hossein","family":"Nezhad","sequence":"additional","affiliation":[{"name":"Student Research Committee Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1288-2277","authenticated-orcid":false,"given":"Zohreh","family":"Shahhosseini","sequence":"additional","affiliation":[{"name":"Sexual and Reproductive Health Research Center Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmood","family":"Moosazadeh","sequence":"additional","affiliation":[{"name":"Gastrointestinal Cancer Research Center Non\u2010Communicable Diseases Institute, Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6872-481X","authenticated-orcid":false,"given":"Forouzan","family":"Elyasi","sequence":"additional","affiliation":[{"name":"Sexual and Reproductive Health Research Center, Psychiatry and Behavioral Sciences Research Center, Faculty of Medicine, Addiction Institute Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2022.10.040"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.2196\/40201"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.14947"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.5001\/omj.2023.69"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.2304"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/nop2.1341"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2020.102407"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2020.102618"},{"key":"e_1_2_13_10_1","doi-asserted-by":"crossref","unstructured":"N. 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