{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T11:49:22Z","timestamp":1782388162913,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropsychopharm Rep"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This cross\u2010sectional study aimed to investigate the relationship between drinking patterns (combination of the frequency and amount of alcohol consumption) and the possession of multiple metabolic syndrome (MetS) components in non\u2010obese and obese individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data derived from medical examinations, specific health checkup questionnaires, and health insurance claims of 36\u2009006 individuals aged 40\u201364\u2009years from five health insurance associations affiliated with Japanese companies were analyzed. Modified Poisson regression analysis was conducted with multiple MetS components as the objective variable, drinking patterns as the explanatory variable, and sex, age, weight gain \u2265\u200910\u2009kg since the age of 20\u2009years, and lifestyle habits except for drinking patterns as adjustment variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Drinking patterns associated with a high risk of possessing multiple MetS components were \u201ceveryday drinking\u201d \u2265\u200920\u2009g\/day and \u201csometimes drinking\u201d \u2265\u200940\u2009g\/day in non\u2010obese individuals and \u201ceveryday drinking\u201d \u2265\u200960\u2009g\/day in obese individuals. Across these risky drinking patterns, the prevalence ratios for the possession of multiple MetS components were higher in non\u2010obese individuals than in obese individuals. Conversely, drinking patterns associated with a lower risk of possessing multiple MetS components were \u201ceveryday drinking &lt;\u200920\u2009g\/day\u201d in non\u2010obese individuals and \u201csometimes drinking &lt;\u200920\u2009g\/day\u201d and \u201ceveryday drinking &lt;\u200920\u2009g\/day\u201d in obese individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Non\u2010obese individuals, even when drinking less frequently and in smaller amounts, showed a higher risk of possessing multiple MetS components than obese individuals, underscoring the importance of supporting reduced alcohol consumption among non\u2010obese individuals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/npr2.70105","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T05:41:08Z","timestamp":1773639668000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Alcohol Drinking Patterns and Multiple Metabolic Syndrome Components in Non\u2010Obese and Obese Individuals"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1517-5815","authenticated-orcid":false,"given":"Ayako","family":"Kikuchi","sequence":"first","affiliation":[{"name":"Graduate School of Comprehensive Human Sciences University of Tsukuba  Tsukuba\u2010shi Japan"},{"name":"Research and Development Center for Lifestyle Innovation University of Tsukuba  Tsukuba\u2010shi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9168-9218","authenticated-orcid":false,"given":"Hisashi","family":"Yoshimoto","sequence":"additional","affiliation":[{"name":"Research and Development Center for Lifestyle Innovation University of Tsukuba  Tsukuba\u2010shi Japan"},{"name":"Department of Family Medicine, General Practice and Community Health, Institute of Medicine University of Tsukuba  Tsukuba\u2010shi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5287-5771","authenticated-orcid":false,"given":"Takafumi","family":"Monma","sequence":"additional","affiliation":[{"name":"Institute of Health and Sport Sciences University of Tsukuba  Tsukuba\u2010shi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakiko","family":"Ozawa","sequence":"additional","affiliation":[{"name":"Institute of Health and Sport Sciences University of Tsukuba  Tsukuba\u2010shi 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