{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:51:58Z","timestamp":1791276718090,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neuropsychopharm Rep"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Electroconvulsive therapy (ECT) is considered relatively safe and effective for severe psychiatric disorders during pregnancy, but evidence regarding neuromuscular blockers for ECT in pregnancy remains limited. We report a 30\u2010year\u2010old primigravida admitted at 30\u2009weeks of gestation with severe major depressive disorder and persistent suicidal ideation despite pharmacotherapy. ECT was initiated at 32\u2009weeks and 2\u2009days of gestation. The first five sessions used succinylcholine. Owing to a nationwide shortage in Japan, the muscle relaxant was switched to rocuronium from the sixth session, with neostigmine and atropine used for reversal during the two antepartum rocuronium sessions. Serial cardiotocographic monitoring before and after each of the seven antepartum ECT sessions showed a transient decrease in fetal heart rate variability after ECT in all sessions and a transient increase in fetal heart rate baseline in five of the seven sessions (Sessions 1, 2, 3, 5, and 7), while fetal well\u2010being was maintained throughout. Spontaneous vaginal delivery occurred at 37\u2009weeks and 0\u2009days, five days after the seventh ECT session. The infant developed respiratory failure shortly after birth and required ventilatory support for two days, but subsequently recovered without complications. Postpartum ECT was resumed for five additional sessions using rocuronium reversed with sugammadex, and the patient achieved clinical remission. This case suggests the feasibility of rocuronium with neostigmine reversal as an alternative to succinylcholine for ECT during late pregnancy when succinylcholine is unavailable, provided that multidisciplinary management and fetal monitoring are available.<\/jats:p>","DOI":"10.1002\/npr2.70159","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:31:31Z","timestamp":1788413491000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Serial Fetal Heart Rate Monitoring During Electroconvulsive Therapy in Late Pregnancy: A Case Report of Transition From Succinylcholine to Rocuronium Reversed With Neostigmine"],"prefix":"10.1002","volume":"46","author":[{"given":"Katsuichiro","family":"Shimizu","sequence":"first","affiliation":[{"name":"Department of Psychiatry Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6728-5341","authenticated-orcid":false,"given":"Hiroyuki","family":"Muraoka","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6119-7584","authenticated-orcid":false,"given":"Tomoe","family":"Fujita","sequence":"additional","affiliation":[{"name":"Division of Obstetric Anesthesia, Center for Perinatal Care, Child Health and Development Kitasato University Hospital  Sagamihara Japan"},{"name":"Department of Anesthesiology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7262-9040","authenticated-orcid":false,"given":"Kyoko","family":"Hattori","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taiyo","family":"Nishikawa","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Uchitsubo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9807-9789","authenticated-orcid":false,"given":"Daigo","family":"Ochiai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kitasato University School of Medicine  Sagamihara 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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737-013-0389-0"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000330"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000116689.75396.5f"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00124509-200006000-00007"},{"key":"e_1_2_11_6_1","volume-title":"Sukisametoniumu Ch\u016bshazai No Antei Ky\u014dky\u016b Ni Tsuite [Regarding the Stable Supply of Suxamethonium (Succinylcholine) Injection]","author":"Japanese Society of Anesthesiologists","year":"2023"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-011-1095-6"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004305"},{"key":"e_1_2_11_9_1","volume-title":"Statement on Sugammadex During 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