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The purpose of this study was to examine the effect of progressive muscle relaxation exercises and laughter therapy on the mental health and treatment outcomes of women receiving IVF treatment. This parallel\u2010group, randomized controlled trial was conducted in a private IVF center. Participants were randomly assigned to the intervention group (IG;<jats:italic>n<\/jats:italic>\u2009=\u200971) and control group (CG;<jats:italic>n<\/jats:italic>\u2009=\u200970). The IG received progressive muscle relaxation and laughter therapy for 40\u2009min in each session for 3\u20134 sessions, whereas the CG received routine care. Data were obtained from the patient information form, State\u2010Trait Anxiety Inventory, Beck Depression Inventory, and medical records. The questionnaire was completed at recruitment (T1) and oocyte pick\u2010up day (T2). In the evaluation performed on the day of the oocyte pick\u2010up, depression and trait anxiety scores of the IG were found to be lower than those in the CG, and the effect size was small. Group\u2009\u00d7\u2009time interaction was significant for depression (large effect size) and trait anxiety (small effect size). The estradiol levels, the number of oocytes, transfer status, and pregnancy rates (according to a blood test) were similar between groups. Women receiving IVF treatment who received progressive muscle relaxation and laughter therapy demonstrated psychological changes; however, the treatment did not affect medical outcomes.<\/jats:p>","DOI":"10.1002\/nur.22187","type":"journal-article","created":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T23:38:51Z","timestamp":1633390731000},"page":"945-956","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Effectiveness of progressive muscle relaxation and laughter therapy on mental health and treatment outcomes in women undergoing in vitro fertilization: A randomized controlled trial"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7278-2094","authenticated-orcid":false,"given":"Sibel","family":"Kiyak","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Nursing, Seydi\u015fehir Kamil Akkanat Faculty of Health Sciences Necmettin Erbakan University Seydi\u015fehir Konya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9496-8749","authenticated-orcid":false,"given":"Deniz","family":"Kocoglu\u2010Tanyer","sequence":"additional","affiliation":[{"name":"Department of Public Health Nursing, Faculty of Nursing Selcuk University Konya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0242024"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.21608\/ejhc.2021.150264"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-012-9904-x"},{"key":"e_1_2_10_5_1","unstructured":"Anu C. 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