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In this randomized controlled trial, the effectiveness of the Technology\u2010based Comprehensive Cardiac Rehabilitation Therapy (TaCT) electronic cardiac rehabilitation\u00a0(eCR) intervention on functional capacity, risk factors, quality of life, heart\u2010health behaviors, symptoms, and morbidity will be tested among women with CVD in a middle\u2010income country. Following a pilot study, a single\u2010center, single\u2010blinded, 2 parallel\u2010arm (1:1 SNOSE) superiority trial comparing an eCR intervention (TaCT) to usual care, with assessments pre\u2010intervention and at 3 and 6 months will be undertaken. One hundred adult women will be recruited. Permuted block (size 10) randomization will be applied. The 6\u2010month intervention comprises an app, website, SMS texts with generic heart\u2010health management advice, and bi\u2010weekly 1:1 telephone calls with a nurse trainee. 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If results of this novel trial of women\u2010focused eCR in a middle\u2010income country demonstrate clinically\u2010significant increases in functional capacity, this could represent an important development for the field considering this would be an important outcome for women and would translate to lower mortality.<\/jats:p>","DOI":"10.1002\/nur.22276","type":"journal-article","created":{"date-parts":[[2022,11,13]],"date-time":"2022-11-13T05:48:50Z","timestamp":1668318530000},"page":"13-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Technology\u2010based Comprehensive Cardiac Rehabilitation Therapy (TaCT) for women with cardiovascular disease in a middle\u2010income setting: A randomized controlled trial protocol"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1141-2356","authenticated-orcid":false,"given":"Henita Joshna","family":"Menezes","sequence":"first","affiliation":[{"name":"Department of Obstetric and Gynecological Nursing, Manipal College of Nursing Manipal Academy of Higher Education Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3842-2650","authenticated-orcid":false,"given":"Sonia R. 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