{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T10:45:40Z","timestamp":1768473940369,"version":"3.49.0"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Research in Nursing &amp; Health"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In\u2010hospital electrocardiographic (ECG) monitors are typically configured to alarm for premature ventricular complexes (PVCs) due to the potential association of PVCs with ventricular tachycardia (VT). However, no contemporary hospital\u2010based studies have examined the association of PVCs with VT. Hence, the benefit of PVC monitoring in hospitalized patients is largely unknown. This secondary analysis used a large PVC alarm data set to determine whether PVCs identified during continuous ECG monitoring were associated with VT, in\u2010hospital cardiac arrest (IHCA), and\/or death in a cohort of adult intensive care unit patients. Six PVC types were examined (i.e., isolated, bigeminy, trigeminy, couplets, R\u2010on\u2010T, and run PVCs) and were compared between patients with and without VT, IHCA, and\/or death. Of 445 patients, 48 (10.8%) had VT; 11 (2.5%) had IHCA; and 49 (11%) died. Isolated and run PVC counts were higher in the VT group (<jats:italic>p<\/jats:italic>\u2009=\u20090.03 both), but group differences were not seen for the other four PVC types. The regression models showed no significant associations between any of the six PVC types and VT or death, although confidence intervals were wide. Due to the\u00a0small number of cases, we were unable to test for associations between PVCs and IHCA. Our findings suggest that we should question the clinical relevance of activating PVC alarms as a forewarning of VT, and more work should be done with larger sample sizes. A more precise characterization of clinically relevant PVCs that might be associated with VT is warranted.<\/jats:p>","DOI":"10.1002\/nur.22314","type":"journal-article","created":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T02:43:35Z","timestamp":1682995415000},"page":"425-435","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of premature ventricular complexes during in\u2010hospital ECG monitoring as a predictor of ventricular tachycardia in an intensive care unit cohort"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0756-5720","authenticated-orcid":false,"given":"Sukardi","family":"Suba","sequence":"first","affiliation":[{"name":"School of Nursing University of Rochester Rochester New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J.","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Medicine, and Office of Research, School of Nursing, University of California San Francisco (UCSF) San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirsten E.","family":"Fleischmann","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Medicine, University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hildy","family":"Schell\u2010Chaple","sequence":"additional","affiliation":[{"name":"Center for Nursing Excellence &amp; Innovation UCSF Medical Center San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory M.","family":"Marcus","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Medicine, University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priya","family":"Prasad","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Medicine, University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Hu","sequence":"additional","affiliation":[{"name":"Nell Hodgson Woodruff School of Nursing, Biomedical Informatics, School of Medicine, and Computer Science, College of Arts and Sciences Emory University Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Badilini","sequence":"additional","affiliation":[{"name":"Department of Physiological Nursing, Center for Physiologic Research, School of Nursing, University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele M.","family":"Pelter","sequence":"additional","affiliation":[{"name":"Department of Physiological Nursing, Center for Physiologic Research, School of Nursing, University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5]]},"reference":[{"issue":"13","key":"e_1_2_11_2_1","first-page":"272","article-title":"2017 AHA\/ACC\/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: A report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines\u00a0and the Heart Rhythm Society","volume":"138","author":"Al\u2010Khatib S. M.","year":"2018","journal-title":"Circulation"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cnc.2016.04.004"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9149(99)00734-1"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2345\/0899-8205-49.3.214"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2015.08.001"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2019.06.032"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192704"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110274"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.33963\/KP.a2021.0182"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9149(02)03424-0"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19960229)15:4<361::AID-SIM168>3.0.CO;2-4"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1198\/000313001300339897"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118548387"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0735-1097(83)80226-5"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.4065\/84.3.289"},{"issue":"7","key":"e_1_2_11_17_1","first-page":"1372","article-title":"Evaluation of multiple imputation with large proportions of missing data: How much is too much?","volume":"50","author":"Lee J. H.","year":"2021","journal-title":"Iranian Journal of Public Health"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(67)90027-6"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.042434"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-0620(66)80021-X"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9149(77)80033-7"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bspc.2015.01.008"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.4037\/ccn2020363"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.08.020"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.05.077"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu194"},{"key":"e_1_2_11_27_1","unstructured":"R Core Team. (2020). R: A language and environment for statistical computing. R Foundation for Statistical Computing.\u00a0https:\/\/www.R-project.org\/"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197710062971404"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000527"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/NCQ.0000000000000335"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(20000430)19:8<1059::AID-SIM412>3.0.CO;2-0"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0261712"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.16408"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198908103210629"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1201\/9780429492259"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v045.i03"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2009.03.017"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1997.tb00997.x"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwk052"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(85)90485-5"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.3177"},{"key":"e_1_2_11_42_1","unstructured":"Woosley R. L. Heise C. W. Gallo T. Tate J. Woosley D. &Romero K. A.(n.d.)QTdrugs List. Accessed September 9 2020.https:\/\/www.CredibleMeds.org"}],"container-title":["Research in Nursing &amp; Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/nur.22314","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T10:33:03Z","timestamp":1692268383000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/nur.22314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1002\/nur.22314"],"URL":"https:\/\/doi.org\/10.1002\/nur.22314","archive":["Portico"],"relation":{},"ISSN":["0160-6891","1098-240X"],"issn-type":[{"value":"0160-6891","type":"print"},{"value":"1098-240X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"2022-10-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}